Bleomycin (BLM) is a drug used to treat different types of neoplasms. BLM's most severe
adverse effect is lung toxicity, which induces remodeling of lung architecture and loss of …

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with a poor prognosis
and limited treatment options. Many compounds have shown efficacy in preclinical models …

Idiopathic pulmonary fibrosis (IPF) is a type of interstitial pneumonia characterized by
chronic and progressive fibrosis with an unknown etiology. Previous pharmacological …

Multi-walled carbon nanotubes (MWCNTs) are an inhomogeneous group of nanomaterials
that vary in lengths, shapes and types of metal contamination, which makes hazard …

Background The respiratory system represents a major portal of entry for xenobiotics into the
body, whether they be intentionally administered as in the case of drugs and anaesthetics …

Background The intratracheal instillation of bleomycin in mice induces early damage to
alveolar epithelial cells and development of inflammation followed by fibrotic tissue changes …

Objectives Investigating the antipulmonary fibrosis effect of mangiferin from Mangifera indica
and the possible molecular mechanism. Methods In vivo, bleomycin (BLM)-induced …

The respiratory mucosa is responsible for gas exchange and is therefore, of necessity,
exposed to airborne pathogens, allergens, and foreign particles. It has evolved a multi …

ABSTRACT Purpose/Aim of Study: Studies of pulmonary fibrosis (PF) have resulted in DNA
damage, inflammatory response, and cellular senescence being widely hypothesized to …

1. In this review, the use of precision-cut tissue slices (PCTS) of the liver, kidney, lung and
intestine in fibrosis research are evaluated and future possibilities are discussed. 2. In vivo …