Antioxidants and atherosclerosis: mechanistic aspects

K Malekmohammad, RDE Sewell, M Rafieian-Kopaei - Biomolecules, 2019 - mdpi.com
Atherosclerosis is a chronic inflammatory disease which is a major cause of coronary heart
disease and stroke in humans. It is characterized by intimal plaques and cholesterol …

[HTML][HTML] The macrophage heme-heme oxygenase-1 system and its role in inflammation

V Vijayan, FA Wagener, S Immenschuh - Biochemical pharmacology, 2018 - Elsevier
Abstract Heme oxygenase (HO)-1, the inducible isoform of the heme-degrading enzyme HO,
plays a critical role in inflammation and iron homeostasis. Regulatory functions of HO-1 are …

The roles and mechanisms of actions of vitamin C in bone: new developments

P Aghajanian, S Hall… - Journal of Bone and …, 2015 - academic.oup.com
Vitamin C is an important antioxidant and cofactor that is involved in the regulation of
development, function, and maintenance of several cell types in the body. Deficiencies in …

Targeting the redox balance in inflammatory skin conditions

FA Wagener, CE Carels, DMS Lundvig - International journal of molecular …, 2013 - mdpi.com
Reactive oxygen species (ROS) can be both beneficial and deleterious. Under normal
physiological conditions, ROS production is tightly regulated, and ROS participate in both …

Vitamin C: a wound healing perspective

J Moores - British journal of community nursing, 2013 - magonlinelibrary.com
Vitamin C, also known as ascorbic acid (AA), is involved in all phases of wound healing. In
the inflammatory phase it is required for neutrophil apoptosis and clearance. During the …

Vitamin E: an overview of major research directions

JM Zingg - Molecular aspects of medicine, 2007 - Elsevier
During the last 90 years since the discovery of vitamin E, research has focused on different
properties of this molecule, the focus often depending on the specific techniques and …

Vitamin E: regulatory role on signal transduction

JM Zingg - IUBMB life, 2019 - Wiley Online Library
Vitamin E modulates signal transduction pathways by several molecular mechanisms. As a
hydrophobic molecule located mainly in membranes it contributes together with other lipids …

An overview of ascorbic acid biochemistry

A Hacısevki - Journal of Faculty of Pharmacy of Ankara University, 2009 - dergipark.org.tr
Ascorbic acid (vitamin C) is a water-soluble micronutrient required for multiple biological
functions. Ascorbic acid is a cofactor for several enzymes participating in the post …

An insight and update on the analgesic properties of vitamin C

NCSK Chaitanya, A Muthukrishnan… - Journal of Pharmacy …, 2018 - journals.lww.com
Pain is an unpleasant subjective feeling having implications on both physical and mental
realm. Multiple dimensions of pain involving behavioral, spiritual, emotional, and cognitive …

Current advances on the phytochemical composition, pharmacologic effects, toxicology, and product development of Phyllanthi Fructus

X Yan, Q Li, L Jing, S Wu, W Duan, Y Chen… - Frontiers in …, 2022 - frontiersin.org
Phyllanthi Fructus (PF), the edible fruits of Phyllanthus emblica L., serves as an important
resource for some health products, foods and drugs due to its high safety and sufficient …