Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433

S Monro, KL Colon, H Yin, J Roque III, P Konda… - Chemical …, 2018 - ACS Publications
Transition metal complexes are of increasing interest as photosensitizers in photodynamic
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …

Quantitative wave function analysis for excited states of transition metal complexes

S Mai, F Plasser, J Dorn, M Fumanal, C Daniel… - Coordination Chemistry …, 2018 - Elsevier
The character of an electronically excited state is one of the most important descriptors
employed to discuss the photophysics and photochemistry of transition metal complexes. In …

Methods to explore cellular uptake of ruthenium complexes

CA Puckett, JK Barton - Journal of the American Chemical Society, 2007 - ACS Publications
The cellular uptake of a series of dipyridophenazine (dppz) complexes of Ru (II) was
examined by flow cytometry. The complexes, owing to their facile synthesis, stability, and …

Marked improvement in photoinduced cell death by a new tris-heteroleptic complex with dual action: singlet oxygen sensitization and ligand dissociation

BA Albani, B Pena, NA Leed… - Journal of the …, 2014 - ACS Publications
The new tris-heteroleptic complex [Ru (bpy)(dppn)(CH3CN) 2] 2+(3, bpy= 2, 2′-bipyridine,
dppn= benzo [i] dipyrido [3, 2-a; 2′, 3′-c] phenazine) was synthesized and characterized …

KiMoPack: A python Package for Kinetic Modeling of the Chemical Mechanism

C Müller, T Pascher, A Eriksson… - The Journal of …, 2022 - ACS Publications
Herein, we present KiMoPack, an analysis tool for the ki netic mo deling of transient
spectroscopic data. KiMoPack enables a state-of-the-art analysis routine including data …

Efficient DNA photocleavage by [Ru (bpy) 2 (dppn)] 2+ with visible light

Y Sun, LE Joyce, NM Dickson, C Turro - Chemical communications, 2010 - pubs.rsc.org
The population and reactivity of two low-lying excited states in [Ru (bpy) 2 (dppn)] 2+(bpy= 2,
2′-bipyridine, dppn= benzo [i] dipyrido [3, 2-a: 2′, 3′-c] phenazine), a weakly emissive …

Ru(II) Complexes of New Tridentate Ligands: Unexpected High Yield of Sensitized 1O2

Y Liu, R Hammitt, DA Lutterman, LE Joyce… - Inorganic …, 2009 - ACS Publications
Ru (II) complexes possessing new tridentate ligands with extended π systems, pydppx (3-
(pyrid-2′-yl)-11, 12-dimethyl-dipyrido [3, 2-a: 2′, 3′-c] phenazine) and pydppn (3-(pyrid …

Environmental effects on the photophysics of transition metal complexes with dipyrido [2, 3-a: 3′, 2′-c] phenazine (dppz) and related ligands

AW McKinley, P Lincoln, EM Tuite - Coordination Chemistry Reviews, 2011 - Elsevier
This review primarily covers studies of ruthenium (II) complexes with the dppz (dipyrido [2, 3-
a: 3′, 2′-c] phenazine) ligand; in solution, in polymers and surfactant/lipid media, and …

[Ru(bpy)2dppz]2+ Light-Switch Mechanism in Protic Solvents as Studied through Temperature-Dependent Lifetime Measurements

MK Brennaman, TJ Meyer… - The Journal of Physical …, 2004 - ACS Publications
Temperature-dependent excited-state lifetime measurements have been performed on four
different Ru (II)-based dppz compounds in protic and aprotic solvents. This work supports …

Photochemically active DNA-intercalating ruthenium and related complexes–insights by combining crystallography and transient spectroscopy

CJ Cardin, JM Kelly, SJ Quinn - Chemical science, 2017 - pubs.rsc.org
Recent research on the study of the interaction of ruthenium polypyridyl compounds and
defined sequence nucleic acids is reviewed. Particular emphasis is paid to complexes [Ru …