Advanced glycation end products: new clinical and molecular perspectives

J Salazar, C Navarro, Á Ortega, M Nava… - International journal of …, 2021 - mdpi.com
Diabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first
century due to its high mortality rates caused mainly due to its complications; therefore, the …

Non-enzymatic glycation mediated structure–function changes in proteins: case of serum albumin

S Awasthi, NT Saraswathi - RSC advances, 2016 - pubs.rsc.org
Albumin, a major plasma protein with extraordinary ligand binding properties, transports
various ligands ranging from drugs, hormones, fatty acids, and toxins to different tissues and …

Study of the dielectric function of aqueous solutions of glucose and albumin by THz time-domain spectroscopy

MM Nazarov, OP Cherkasova… - Quantum …, 2016 - iopscience.iop.org
We report a study of aqueous solutions of glucose and bovine serum albumin using THz
time-domain spectroscopy. To describe the permittivity of the solutions of these substances …

Magnetite nanoparticles for stem cell labeling with high efficiency and long-term in vivo tracking

N Guldris, B Argibay, J Gallo, R Iglesias-Rey… - Bioconjugate …, 2017 - ACS Publications
Superparamagnetic iron oxide nanoparticles (SPIO-PAA), ultrasmall iron oxide
nanoparticles (USPIO-PAA), and glucosamine-modified iron oxide nanoparticles (USPIO …

Fewer exposed lysine residues may explain relative resistance of chicken serum albumin to in vitro protein glycation in comparison to bovine serum albumin

CM Anthony-Regnitz, AE Wilson, KL Sweazea… - Journal of Molecular …, 2020 - Springer
Protein glycation and formation of advanced glycation end products is associated with
several diseases resulting from high blood glucose concentrations. Plasma albumin is …

Glyoxal induced glycative insult suffered by immunoglobulin G and fibrinogen proteins: A comparative physicochemical characterization to reveal structural …

S Alouffi, U Shahab, S Khan, M Khan, A Khanam… - International Journal of …, 2022 - Elsevier
Glycation of proteins results in structural alteration, functional deprivation, and generation of
advanced glycation end products (AGEs). Reactive oxygen species (ROS) that are …

Glycation of immunoglobulin-G from pentose sugar: a cause for structural perturbations

F Alenazi, M Saleem, AS Syed Khaja… - Current Protein and …, 2022 - ingentaconnect.com
Background: Glycation of immunoglobulin-G (IgG) molecules with monosaccharides may
cause significant structural disability, thus resulting in their loss of function. The …

Glycation resistance and life-history traits: lessons from non-conventional animal models

C Duval, F Criscuolo, F Bertile - Biology Letters, 2024 - royalsocietypublishing.org
Glycation reactions play a key role in the senescence process and are involved in numerous
age-related pathologies, such as diabetes complications or Alzheimer's disease. As a result …

The neoepitopes on methylglyoxal‐(MG‐) glycated fibrinogen generate autoimmune response: its role in diabetes, atherosclerosis, and diabetic atherosclerosis …

S Rehman, J Song, M Faisal, AA Alatar… - Oxidative Medicine …, 2021 - Wiley Online Library
Objectives. In diabetes mellitus, hyperglycemia‐mediated nonenzymatic glycosylation of
fibrinogen protein plays a crucial role in the pathogenesis of micro‐and macrovascular …

Detection of Circulating Auto‐Antibodies Against Ribosylated‐LDL in Diabetes Patients

F Akhter, M Salman Khan, M Faisal… - Journal of Clinical …, 2017 - Wiley Online Library
Background This study analyzes effect of glycation on ApoB‐100 residues by D‐ribose as D‐
ribosylated‐glycated LDL might be responsible for the cause of diabetes mellitus because of …