Novel 6-Aminoquinazolinone derivatives as potential cross GT1-4 HCV NS5B inhibitors
Chronic hepatitis C virus (HCV) infections are a worldwide medical problem responsible for
diverse types of liver diseases. The NS5B polymerase enzyme has become a very …
diverse types of liver diseases. The NS5B polymerase enzyme has become a very …
Anthranilic acids from isatin: an efficient, versatile and environmentally friendly method
GF Rio, BV Silva, ST Martinez, AC Pinto - Anais da Academia …, 2015 - SciELO Brasil
This paper describes the preparation of a series of 16 anthranilic acids in yields ranging
from 51 to 97%, by treating the isatins with NaOH and H2O2. Independently of the nature of …
from 51 to 97%, by treating the isatins with NaOH and H2O2. Independently of the nature of …
Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1
R Kirk, A Ratcliffe, G Noonan, M Uosis-Martin… - RSC Medicinal …, 2020 - pubs.rsc.org
The alarming reduction in drug effectiveness against bacterial infections has created an
urgent need for the development of new antibacterial agents that circumvent bacterial …
urgent need for the development of new antibacterial agents that circumvent bacterial …
[图书][B] Synthesis of Metal Complexes Supported by Ferrocene-based Ligands for Tandem Catalysis and Applications toward Liquid Cell Quantum Sensing
Y Shen - 2023 - search.proquest.com
Developing methodologies to synthesize high-value products efficiently from simple
substrates with control over the reactivity and selectivity is highly favored by the chemical …
substrates with control over the reactivity and selectivity is highly favored by the chemical …
Electrosynthesis in flow reactors. Part 1: Anodic deprotection of nitrogen containing compounds. Part 2: Cathodic cyclisation of aryl halides
A Teuten - 2021 - eprints.soton.ac.uk
Flow electrosynthesis is an important field of chemistry, with the ability to deliver improved
selectivity, higher yields, and higher productivities compared to both batch electrochemistry …
selectivity, higher yields, and higher productivities compared to both batch electrochemistry …
Enantioselective Synthesis of Drug-like Molecules via Axially-chiral Intermediates
GM Richoux Jr - 2016 - vtechworks.lib.vt.edu
The self-regeneration of stereocenters via stereolabile axially-chiral intermediates
(SRSvSACI) is a synthetic strategy in which the configuration of a starting material …
(SRSvSACI) is a synthetic strategy in which the configuration of a starting material …