Although there has been considerable progress in the development of engineering
principles for synthetic biology, a Substantial challenge is the construction of robust circuits …

Feeding bacterially-secreted GLP-1 intestinally to diabetic mice can cause glucose-
responsive insulin production, reduc-35 ing blood glucose levels significantly. The …

The present invention relates to a method for fine-tuning gene expression levels using a
synthetic regulatory sRNA in a prokaryotic cell. The present invention can simultaneously …

Genetically engineered cells and microorganisms are pro vided for preventing or
ameliorating diseases through geneti cally engineered quorum signaling. Therapeutic …

V cholerae El Tor serotypes are largely responsible for outbreaks of cholera in the
developing world. The infection cycle for Some strains of V. cholerae is coordinated, at least …

Recombinant cells and methods are provided that relate to the use of isolated, engineered
recombinant cells to directly or indirectly treat diseases or disorders in a mammalian host …