The kidneys play a key role in maintaining total body homeostasis. The complexity of this
task is reflected in the unique architecture of the organ. Ureteral obstruction greatly affects …

The physiological process of biomineralization is complex and deviation from it leads to a
variety of diseases. Progress in the past 10 years has enhanced understanding of the …

Kidney stones, represented by the calcium oxalate (CaOx) type, are highly prevalent and
recrudescent. Cumulative evidence shows regular consumption of lemonade intervenes …

Background Gut microbiota, particularly Oxalobacter formigenes, has been previously
reported to be associated with kidney stones. However, the conflicting results from both …

Background Evidence describing the relationship between short-term temperature exposure
and kidney-related conditions is insufficient. It remains unclear how temperature …

Kidney failure, the decrease of kidney function below a threshold necessary to support life, is
a major cause of morbidity and mortality. We performed a genome-wide association study …

Nephrolithiasis is highly prevalent and associated with the increased risk of kidney cancer.
The tumor suppressor von Hippel-Lindau (VHL) is critical for renal cancer development …

Kidney stone disease (KSD) is a complex disorder with high heritability and prevalence. We
performed a large genome-wide association study (GWAS) meta-analysis for KSD to date …

Assessing the effects of heavy metals (HMs) on kidney stone is often limited to analyzing
individual metal exposures, with studies on the effects of exposure to mixtures of HMs being …

The increased global incidence of chronic metabolic diseases, a vital threat to human health
and a burden on our healthcare systems, includes a series of clinical metabolic syndromes …