Cisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia caused
by resistance to insulin action, inadequate insulin secretion, or excessive glucagon …

Septic acute kidney injury (AKI) is characterized by inflammation. Pyroptosis often occurs
during AKI and is associated with the development of septic AKI. This study found that …

Abstract The N6-methyladenosine (m6A) modification is regulated by methylases, commonly
referred to as “writers,” and demethylases, known as “erasers,” leading to a dynamic and …

In hospitals, contrast‐induced acute kidney injury (CI‐AKI) is a major cause of renal failure.
This study evaluates berberine's (BBR) renal protection and its potential HDAC4 …

Epigenetic modifications have received increasing attention and have been shown to be
extensively involved in kidney development and disease progression. Among them, the …

Sepsis is defined as a dysregulated immune response to infection that leads to multiple
organ dysfunction. To date, though a growing body of knowledge has gained insight into the …

Aim: To identify the alterations of N6-methyladenosine (m6A) RNA profiles in cisplatin-
induced acute kidney injury (Cis-AKI) in mice. Materials and Methods: The total level of m6A …

Chemical modifications are a specific and efficient way to regulate the function of biological
macromolecules. Among them, RNA molecules exhibit a variety of modifications that play …

Although great efforts have been made to elucidate the pathological mechanisms of renal
diseases and potential prevention and treatment targets that would allow us to retard kidney …