Epstein–Barr virus: how its lytic phase contributes to oncogenesis

Q Rosemarie, B Sugden - Microorganisms, 2020 - mdpi.com
Epstein–Barr Virus (EBV) contributes to the development of lymphoid and epithelial
malignancies. While EBV's latent phase is more commonly associated with EBV-associated …

Immune regulation in Epstein-Barr virus-associated diseases

R Khanna, SR Burrows, DJ Moss - Microbiological reviews, 1995 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a member of the human herpesvirus family and, like many other
herpesviruses, maintains a lifelong latent association with B lymphocytes and a permissive …

Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes

J Sample, L Young, B Martin, T Chatman… - Journal of …, 1990 - Am Soc Microbiol
The two Epstein-Barr virus (EBV) types, EBV-1 and EBV-2, are known to differ in their EBNA-
2 genes, which are 64 and 53% identical in their nucleotide and predicted amino acid …

Geographical prevalence of two types of Epstein-Barr virus

U Zimber, HK Adldinger, GM Lenoir, M Vuillaume… - Virology, 1986 - Elsevier
The Jijoye EBV strain is characterized by a substitution of 1.8 kb in the C-terminal part of the
EBNA 2 gene compared to B95-8 or M-ABA virus. This made it possible to construct …

Treatment of solid organ transplant recipients with autologous Epstein Barr virus–specific cytotoxic T lymphocytes (CTLs)

B Savoldo, JA Goss, MM Hammer, L Zhang, T Lopez… - Blood, 2006 - ashpublications.org
We have investigated the in vivo safety, efficacy, and persistence of autologous Epstein Barr
virus (EBV)–specific cytotoxic T lymphocytes (CTLs) for the treatment of solid organ …

First days in the life of naive human B lymphocytes infected with Epstein-Barr virus

D Pich, P Mrozek-Gorska, M Bouvet, A Sugimoto… - MBio, 2019 - Am Soc Microbiol
Epstein-Barr virus (EBV) infects and activates resting human B lymphocytes, reprograms
them, induces their proliferation, and establishes a latent infection in them. In established …

New type B isolates of Epstein—Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas

LS Young, QY Yao, CM Rooney… - Journal of General …, 1987 - microbiologyresearch.org
Summary All Epstein-Barr virus (EBV) isolates can be classified as type A or type B
depending upon the identity of their EBV nuclear antigen (EBNA) 2 protein. The great …

EBV and apoptosis: the viral master regulator of cell fate?

L Fitzsimmons, GL Kelly - Viruses, 2017 - mdpi.com
Epstein–Barr virus (EBV) was first discovered in cells from a patient with Burkitt lymphoma
(BL), and is now known to be a contributory factor in 1–2% of all cancers, for which there are …

Epstein-Barr virus and human diseases: recent advances in diagnosis

M Okano, GM Thiele, JR Davis… - Clinical microbiology …, 1988 - Am Soc Microbiol
Since the discovery of Epstein-Barr virus (EBV) from a cultured Burkitt's lymphoma cell line
in 1964, the virus has been associated with Burkitt's lymphoma, nasopharyngeal carcinoma …

Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, Jijoye

M Rabson, L Gradoville, L Heston, G Miller - Journal of Virology, 1982 - Am Soc Microbiol
The P3J-HR-1 strain of Epstein-Barr virus (EBV) fails to immortalize human lymphocytes. We
wished to understand the nature of the genomic alterations which correlated with the loss of …