Targeted therapy for lung cancer: Beyond EGFR and ALK

M Herrera‐Juárez, C Serrano‐Gómez… - Cancer, 2023 - Wiley Online Library
Precision oncology comprises the set of strategies that aim to design the best cancer
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …

Precision medicine in urothelial carcinoma: Current markers to guide treatment and promising future directions

EJ Miller, MD Galsky - Current Treatment Options in Oncology, 2023 - Springer
Opinion statement The treatment landscape for urothelial cancer has changed dramatically
in the last 10 years, with the approval of several new treatments. At the same time, profiling …

Evaluating Diff‐Quik cytology smears for large‐panel mutation testing in lung cancer—Predicting DNA content and success with low‐malignant‐cellularity samples

DI Fielding, AJ Dalley, M Singh… - Cancer …, 2023 - Wiley Online Library
Background Cytology smears are commonly collected during endobronchial ultrasound–
guided transbronchial needle aspiration (EBUS TBNA) procedures but are rarely used for …

Trends in real-world biomarker testing and overall survival in US patients with advanced non-small-cell lung cancer

N Wu, W Ge, RGW Quek, M Gleeson, JF Pouliot… - Future …, 2022 - Taylor & Francis
Background: Trends/outcomes associated with National Comprehensive Cancer Network
(NCCN)-recommended biomarker testing to guide advanced non-small-cell lung cancer …

The Challenges and Opportunities of the Implementation of Comprehensive Genomic Profiling in Everyday Clinical Practice with Non-Small Cell Lung Cancer …

D Čerina, K Krpina, M Jakopović, N Dedić Plavetić… - Cancers, 2023 - mdpi.com
Simple Summary Precision medicine has reached its current peak in non-small cell lung
cancer (NSCLC), with a constantly growing number of predictive biomarkers and new …

Optimizing molecular testing of lung cancer needle biopsy specimens: potential solutions from an interdisciplinary qualitative study

FJ Fintelmann, NA Martin, I Tahir, EM Quinn… - Respiratory …, 2023 - Springer
Background Molecular testing can detect actionable genomic alterations and tumor cell
surface proteins in patients with non–small cell lung cancer (NSCLC). However, utilization …

Cost-effectiveness of large-panel next-generation sequencing in guiding first-line treatment decisions for patients with nonsquamous advanced non–small cell lung …

IM Abbass, DM Sheinson, A Shah, A Gondos… - Journal of Managed …, 2024 - jmcp.org
BACKGROUND: Clinical practice guidelines recommend broad-panel genomic profiling to
identify actionable genomic alterations for patients with advanced non–small cell lung …

Suitability of respiratory endoscopy for sampling malignant thoracic tumors for comprehensive genomic profiling

K Fujimoto, Y Matsumoto, T Imabayashi… - Cancer …, 2023 - Wiley Online Library
Comprehensive genomic profiling (CGP) is implemented to detect actionable gene
aberrations and design matched therapies. Although malignant thoracic tumors are …

Ancestry-, Sex-, and Age-Based Differences of Gene Alterations in NSCLC: From the Real-World Data of Cancer Genomic Profiling Tests

K Miura, T Shukuya, R Greenstein, B Kaplan… - Journal of the National …, 2024 - jnccn.org
Background: Some genomic alterations in non–small cell lung cancer (NSCLC) are known
to differ according to race, sex, or age. These studies have been limited in sample size and …

Real-world treatment patterns and outcomes of first-line immunotherapy among patients with advanced nonsquamous Nsclc harboring Braf, Met, or Her2 alterations

MC Garassino, S Oskar, A Arunachalam, K Zu… - JTO Clinical and …, 2023 - Elsevier
Introduction Data on utilization and clinical outcomes of programmed cell death protein or
programmed death-ligand 1 (PD-[L] 1) inhibitors in NSCLC with uncommon oncogenic …