Although some tumor has become a curable disease for many patients, involvement of the
central nervous system (CNS) is still a major concern. The blood–brain barrier (BBB), a …

Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …

Today, cancer treatment is an important issue in the medical world due to the challenges
and side effects of ongoing treatment procedures. Current methods can be replaced with …

Carbon is the most abundant and structural building-block element of life. It is nonmetallic,
but bears the unique ability of self-binding and associating other elements to form …

Polymer-based nanoparticles of tailored size, morphology, and surface properties have
attracted increasing attention as carriers for drugs, biomolecules, and genes. By protecting …

This advanced review describes the anatomical and physiological barriers and mechanisms
impacting nanomedicine translocation from the nasal cavity directly to the brain. There are …

Drug delivery into the brain has for long been a huge challenge as the blood–brain barrier
(BBB) offers great resistance to entry of foreign substances (with drugs inclusive) into the …

Andrographis paniculata is a well-known Asian medicinal plant with a major
phytoconstituent of diterpene lactones, such as andrographolide, 14-deoxyandrographolide …

Recently, several nutraceutical products are being explored to validate their neuroprotective
claims as well as clinical prospects in terms of balancing neurosignaling mechanisms …

Parkinson's disease (PD) is the second most common progressive neurodegenerative
disease that promotes neuronal cell death. The primary treatment strategy for Parkinson's …