Harnessing plant biotechnology-based strategies for in vitro galanthamine (GAL) biosynthesis: A potent drug against Alzheimer's disease

H Kaur, S Chahal, P Jha, MM Lekhak… - Plant Cell, Tissue and …, 2022 - Springer
Medicinal plants are important for improving human health and represent an essential pool
for the identification of novel pharmacological leads. Plant-derived biomolecules have …

Biotechnological approaches to optimize the production of Amaryllidaceae alkaloids

M Koirala, V Karimzadegan, NS Liyanage, N Mérindol… - Biomolecules, 2022 - mdpi.com
Amaryllidaceae alkaloids (AAs) are plant specialized metabolites with therapeutic properties
exclusively produced by the Amaryllidaceae plant family. The two most studied …

[HTML][HTML] Influence of plant growth regulators on in vitro biomass production and biosynthesis of cytotoxic Amaryllidaceae alkaloids in Caliphuria tenera Baker

LMT Chacón, H Leiva, ICZ Vahos, DC Restrepo… - Biocatalysis and …, 2023 - Elsevier
Plants of the Amaryllidoideae subfamily are characterized by the presence of isoquinoline
alkaloids called Amaryllidaceae alkaloids. These compounds have exhibited a broad …

[HTML][HTML] Elicitation Induced α-Amyrin Synthesis in Tylophora indica In Vitro Cultures and Comparative Phytochemical Analyses of In Vivo and Micropropagated Plants

J Mamgain, A Mujib, Y Bansal, B Gulzar, N Zafar… - Plants, 2023 - mdpi.com
Tylophora indica (Burm. f.) Merrill is an endangered medicinal plant that possesses various
active agents, such as tylophorinine, kaempferol, quercetin, α-amyrin and beta-sitosterol …

Lycorine as a lead molecule in the treatment of cancer and strategies for its biosynthesis using the in vitro culture technique

S Sena, H Kaur, V Kumar - Phytochemistry Reviews, 2024 - Springer
Medicinal plants are used by many of the global population because they are safe and
effective alternative to other treatments. Over the last few decades, using plant cells to …

Biotic elicitation for enhanced production of plumbagin in regenerated shoot cultures of Plumbago zeylanica using response surface methodology

K Katoch, S Gupta, AP Gupta, P Goyal, R Devi… - Plant Cell, Tissue and …, 2022 - Springer
Plumbagin is the major secondary metabolite found in Plumbago species, it exhibit a wide
variety of pharmaceutical activities. The initial focus of this study was to establish a suitable …

Comparative Analysis of Primary and Secondary Metabolites in Different In Vitro Tissues of Narcissus tazetta var. chinensis

C Park, R Sathasivam, HJ Yeo, YJ Park, JK Kim… - ACS …, 2024 - ACS Publications
Narcissus tazetta var. chinensis is a perennial monocot plant that is well known for its
pharmaceutical and ornamental uses. This study aimed to understand the changes in the …

Multi-omics revealed molecular mechanism of biphenyl phytoalexin formation in response to yeast extract-induced oxidative stress in Sorbus aucuparia suspension …

Y Li, J Yang, J Zhou, X Wan, J Liu, S Wang, X Ma… - Plant Cell Reports, 2024 - Springer
Key message Yeast extract-induced oxidative stress in Sorbus aucuparia suspension cells
leads to the biosynthesis of various hormones, which activates specific signaling pathways …

[HTML][HTML] Effect of Liquid Culture Systems (Temporary Immersion Bioreactor and Rotary Shaker) Used During Multiplication and Differentiation on Efficiency of …

M Malik, E Tomiak, B Pawłowska - Agronomy, 2024 - mdpi.com
Liquid culture systems, including bioreactors, are valuable tools for the scaling up of
production. Their involvement leads to the automation of the highly efficient, reproducible …

Elicitation strategies for enhanced secondary metabolite synthesis in plant cell cultures and its role in plant defense mechanism

N Selwal, K Supriadi, F Rahayu, D Sukmadjaja… - Plant Gene, 2025 - Elsevier
Plants possess the remarkable ability to thrive in challenging environments by synthesizing
a diverse array of specialized metabolites, which play crucial roles in defense against biotic …