The vertebrate control of locomotion involves all levels of the nervous system from cortex to
the spinal cord. Here, we aim to cover all main aspects of this complex behavior, from the …

Locomotion is a universal motor behavior that is expressed as the output of many integrated
brain functions. Locomotion is organized at several levels of the nervous system, with …

The mesencephalic locomotor region (MLR) is a brain stem area whose stimulation triggers
graded forward locomotion. How MLR neurons recruit downstream vsx2+(V2a) …

Modeling human motor control and predicting how humans will move in novel environments
is a grand scientific challenge. Researchers in the fields of biomechanics and motor control …

The problem of controlling locomotion is an area in which neuroscience and robotics can
fruitfully interact. In this article, I will review research carried out on locomotor central pattern …

In the absence of salient sensory cues to guide behavior, animals must still execute
sequences of motor actions in order to forage and explore. How such successive motor …

The flexibility of locomotor movements requires an accurate control of their start, duration,
and speed. How brainstem circuits encode and convey these locomotor parameters remains …

The vertebrate motor system is equipped with a number of neuronal networks that underlie
different patterns of behaviour, from simple protective reflexes to complex movements. The …

In Parkinson's disease (PD), the loss of midbrain dopaminergic cells results in severe
locomotor deficits, such as gait freezing and akinesia. Growing evidence indicates that these …

The reticular formation in the brainstem controls motor output via axonal projections to the
hindbrain and spinal cord. It remains unclear how individual groups of brainstem neurons …