This Review explores the class of plant-derived macrocyclic peptides called cyclotides. We
include an account of their discovery, characterization, and distribution in the plant kingdom …

Antimicrobial peptides (AMPs) are pinpointed as promising molecules against antibiotic-
resistant bacterial infections. Nevertheless, there is a discrepancy between the AMP …

Plants are extensively used in traditional medicine, and several plant antimicrobial peptides
have been described as potential alternatives to conventional antibiotics. However, after …

Cyclotides are plant-derived cyclic peptides that have a head-to-tail cyclic backbone and
three conserved disulphide bonds that form a cyclic cystine knot motif. They occur in plants …

The emergence of pathogens resistant to conventional antibiotics and the growing interest in
developing alternative natural antimicrobial agents have prompted a search for plant …

For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …

At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …

The growing antimicrobial resistance crisis necessitates the discovery and development of
novel classes of antibiotics if a 'postantibiotic era'is to be avoided. Ribosomally synthesised …

Cyclotides are globular microproteins with a unique head‐to‐tail cyclized backbone,
stabilized by three disulfide bonds forming a cystine knot. This unique circular backbone …

Cyclotides are a novel class of micro-proteins (≈ 30–40 residues long) with a unique
topology containing a head-to-tail cyclized backbone structure further stabilized by three …