[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism

T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis

T Hara, T Takeda, T Takagishi, K Fukue… - The Journal of …, 2017 - Springer
Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …

Changes in plasma free fatty acids associated with type-2 diabetes

A IS Sobczak, C A. Blindauer, A J. Stewart - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid
(FFA) concentrations and an elevated risk of cardiovascular disease. The exact mechanisms …

The role of zinc and zinc homeostasis in macrophage function

H Gao, W Dai, L Zhao, J Min… - Journal of immunology …, 2018 - Wiley Online Library
Zinc has long been recognized as an essential trace element, playing roles in the growth
and development of all living organisms. In recent decades, zinc homeostasis was also …

Unraveling the interaction between FcRn and albumin: opportunities for design of albumin-based therapeutics

KMK Sand, M Bern, J Nilsen, HT Noordzij… - Frontiers in …, 2015 - frontiersin.org
The neonatal Fc receptor (FcRn) was first found to be responsible for transporting antibodies
of the immunoglobulin G (IgG) class from the mother to the fetus or neonate as well as for …

Current understanding of ZIP and ZnT zinc transporters in human health and diseases

T Kambe, A Hashimoto, S Fujimoto - Cellular and molecular life sciences, 2014 - Springer
Abstract Zinc transporters, the Zrt-, Irt-like protein (ZIP) family and the Zn transporter (ZnT)
family transporters, are found in all aspects of life. Increasing evidence has clarified the …

[HTML][HTML] Towards the functional high-resolution coordination chemistry of blood plasma human serum albumin

S Al-Harthi, JI Lachowicz, ME Nowakowski… - Journal of inorganic …, 2019 - Elsevier
Human serum albumin (HSA) is a monomeric, globular, multi-carrier and the most abundant
protein in the blood. HSA displays multiple ligand binding sites with extraordinary binding …

Copper and Zinc Particles as Regulators of Cardiovascular System Function—A Review

K Kitala, D Tanski, J Godlewski… - Nutrients, 2023 - mdpi.com
Copper and zinc are micronutrients that play a crucial role in many cellular pathways, act as
cofactors in enzymatic systems, and hence, modulate enzyme activity. The regulation of …

Zinc and skin biology

Y Ogawa, T Kawamura, S Shimada - Archives of biochemistry and …, 2016 - Elsevier
Of all tissues, the skin has the third highest abundance of zinc in the body. In the skin, the
zinc concentration is higher in the epidermis than in the dermis, owing to a zinc requirement …

Association of zinc deficiency with development of CVD events in patients with CKD

S Nakatani, K Mori, T Shoji, M Emoto - Nutrients, 2021 - mdpi.com
Deficiency of the micronutrient zinc is common in patients with chronic kidney disease
(CKD). The aim of this review is to summarize evidence presented in literature for …