Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise
untreatable types of cancer. Despite encouraging developments in recent years, the limited …

Simple Summary Enteroviruses are considered to be promising oncolytic agents towards a
variety of human cancers. Enteroviruses comprise polioviruses, coxsackieviruses, and …

Background Oncolytic viruses are now well recognized as potential immunotherapeutic
agents against cancer. However, the first FDA-approved oncolytic herpes simplex virus 1 …

Abstract Background and Aim CD155/T‐cell immunoglobulin and ITIM domain (TIGIT)
suppressed anti‐cancer immunity in several cancers, but its roles in colorectal cancer (CRC) …

CD155 is an immunoglobulin-like protein overexpressed in almost all the tumor cells, which
not only promotes proliferation, adhesion, invasion, and migration of tumor cells, but also …

Virotherapy is a potential anticancer therapy that uses viral agents to locate and destroy
cancerous cells. Clinical trials conducted on viruses, both naturally oncolytic and those …

Introduction Poliovirus receptor (PVR) is a tumor promoter and a regulatory checkpoint that
enhances immunosuppression. We investigated PVR expression by applying …

Background/Aim: The CD155/TIGIT axis has recently emerged as a promising
immunotherapeutic target in several malignancies. However, its prognostic relevance within …

Introduction Breast cancer is one of the most common cancers among women in the world.
Different therapeutic strategies such as radiotherapy, chemotherapy and surgery have been …

Oncolytic virotherapy is a promising antitumor strategy which utilizes the lytic nature of viral
replication to kill cancer cells. Oncolytic viruses (OVs) can induce cancer cell death and …