Reactive oxygen species (ROS) in biological systems are transient but essential molecules
that are generated and eliminated by a complex set of delicately balanced molecular …

Tumors strongly depend on their surrounding tumor microenvironment (TME) for growth and
progression, since stromal elements are required to generate the optimal conditions for …

Astragaloside IV (AsIV), an active ingredient isolated from traditional Chinese medicine
astragalus membranaceus, is beneficial to cardiovascular health. This study aimed to …

Abnormal expression of proteins, including catalytic and expression dysfunction, is directly
related to the development of various diseases in living organisms. Reactive oxygen species …

Reactive oxygen species (ROS) are a group of highly active molecules produced by normal
cellular metabolism and play a crucial role in the human body. In recent years, researchers …

The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa)
remains controversial. Previously, we found that plasma exosomal miR-375 is significantly …

The continuous remodeling of the tumor microenvironment (TME) during prostate
tumorigenesis is emerging as a critical event that facilitates cancer growth, progression and …

Drug resistance is the main obstacle to achieving a cure in many cancer patients. Reactive
oxygen species (ROS) are master regulators of cancer development that act through …

Several studies have indicated that cancer-associated fibroblasts (CAFs) could promote
cancer progression in many malignancies. However, the mechanism by which CAFs …

Cancer cells evolve in a very complex tumor microenvironment, composed of several cell
types, among which the endothelial cells are the major actors of the tumor angiogenesis …