Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

NI Mazur, J Terstappen, R Baral, A Bardají… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …

Respiratory syncytial virus disease burden in adults aged 60 years and older in high‐income countries: A systematic literature review and meta‐analysis

M Savic, Y Penders, T Shi, A Branche… - Influenza and other …, 2023 - Wiley Online Library
Background Respiratory syncytial virus (RSV)‐associated acute respiratory infection (ARI) is
an underrecognized cause of illness in older adults. We conducted a systematic literature …

Efficacy and safety of a bivalent RSV prefusion F vaccine in older adults

EE Walsh, G Pérez Marc, AM Zareba… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) infection causes considerable illness in older
adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein–based …

[HTML][HTML] Efficacy and safety of an mRNA-based RSV PreF vaccine in older adults

E Wilson, J Goswami, AH Baqui… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) can cause substantial morbidity and mortality
among older adults. An mRNA-based RSV vaccine, mRNA-1345, encoding the stabilized …

Respiratory syncytial virus infection and novel interventions

AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …

The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study

JG Wildenbeest, MN Billard, RP Zuurbier… - The Lancet …, 2023 - thelancet.com
Background Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants.
The burden of RSV infection in healthy term infants has not yet been established. Accurate …

Rates of medically attended RSV among US adults: a systematic review and meta-analysis

JM McLaughlin, F Khan, E Begier… - Open forum …, 2022 - academic.oup.com
Background Adult respiratory syncytial virus (RSV) vaccines are in the late stages of
development. A comprehensive synthesis of adult RSV burden is needed to inform public …

Underascertainment of respiratory syncytial virus infection in adults due to diagnostic testing limitations: a systematic literature review and meta-analysis

C Onwuchekwa, LM Moreo, S Menon… - The Journal of …, 2023 - academic.oup.com
Background Most observational population-based studies identify respiratory syncytial virus
(RSV) by nasal/nasopharyngeal swab reverse transcriptase real-time PCR (RT-PCR) only …

Estimation of the number of respiratory syncytial virus–associated hospitalizations in adults in the European Union

R Osei-Yeboah, P Spreeuwenberg… - The Journal of …, 2023 - academic.oup.com
Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract
infections in adults that can result in hospitalizations. Estimating RSV-associated …

Incidence of respiratory syncytial virus infection in older adults before and during the COVID-19 pandemic

YJ Juhn, CI Wi, PY Takahashi, E Ryu, KS King… - JAMA network …, 2023 - jamanetwork.com
Importance Little is known about the burden and outcomes of respiratory syncytial virus
(RSV)–positive acute respiratory infection (ARI) in community-dwelling older adults …