Wiskott–Aldrich syndrome protein (WASP) and WASP-family verprolin-homologous protein
(WAVE) family proteins are scaffolds that link upstream signals to the activation of the …

The Wiskott-Aldrich syndrome (WAS) is a rare X-linked disorder with variable clinical
phenotypes that correlate with the type of mutations in the WAS protein (WASP) gene …

Cells have various surface architectures, which allow them to carry out different specialized
functions. Actin microfilaments that are associated with the plasma membrane are important …

The assembly of a branched network of actin filaments provides the mechanical propulsion
that drives a range of dynamic cellular processes, including cell motility. The Arp2/3 complex …

Signal-dependent regulation of actin dynamics is essential for a variety of cellular
processes, including formation of the membrane protrusions required for cell locomotion …

The actin cytoskeleton is a vital component of several key cellular and developmental
processes in eukaryotes. Many proteins that interact with filamentous and/or monomeric …

Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 (WH2) is a small and
widespread actin-binding motif. In the WASP family, WH2 plays a role in filament nucleation …

Burkholderia pseudomallei is a Gram‐negative facultative intracellular pathogen that enters
and escapes from eukaryotic cells using the power of actin polymerization. We have …

The WH2 (WASP homology domain-2) is a small actin monomer-binding motif and is found
in many proteins that regulate the actin cytoskeleton, including the β-thymosins, ciboulot …

Cells have many types of actin structures, which must assemble from a common monomer
pool. Yet, it remains poorly understood how monomers are distributed to and shared …