Viral vector-based gene therapy

X Li, Y Le, Z Zhang, X Nian, B Liu, X Yang - International Journal of …, 2023 - mdpi.com
Gene therapy is a technique involving the modification of an individual's genes for treating a
particular disease. The key to effective gene therapy is an efficient carrier delivery system …

Viral Vectors for the in Vivo Delivery of CRISPR Components: Advances and Challenges

M Asmamaw Mengstie - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and its
accompanying protein (Cas9) are now the most effective, efficient, and precise genome …

Comparison of IgA, IgG, and neutralizing antibody responses following immunization with Moderna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson, and …

T Adjobimey, J Meyer, L Sollberg, M Bawolt… - Frontiers in …, 2022 - frontiersin.org
In an ongoing multinational trial, we obtained blood samples from 365 volunteers vaccinated
with mRNA vaccines (Moderna, BioNTech), viral DNA-vectored vaccines (AstraZeneca …

Immunogenicity of CRISPR therapeutics—Critical considerations for clinical translation

R Ewaisha, KS Anderson - Frontiers in Bioengineering and …, 2023 - frontiersin.org
CRISPR offers new hope for many patients and promises to transform the way we think of
future therapies. Ensuring safety of CRISPR therapeutics is a top priority for clinical …

Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy

SE Ahmadi, M Soleymani, F Shahriyary… - Cancer Gene …, 2023 - nature.com
Gene editing-based therapeutic strategies grant the power to override cell machinery and
alter faulty genes contributing to disease development like cancer. Nowadays, the principal …

Recombinant vaccines in 2022: a perspective from the cell factory

MT de Pinho Favaro, J Atienza-Garriga… - Microbial cell …, 2022 - Springer
The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

Vaccine development against tuberculosis before and after Covid-19

SHE Kaufmann - Frontiers in Immunology, 2023 - frontiersin.org
Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …

Epidemic history and evolution of an emerging threat of international concern, the severe acute respiratory syndrome coronavirus 2

M Giovanetti, F Branda, E Cella… - Journal of Medical …, 2023 - Wiley Online Library
This comprehensive review focuses on the severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2) and its impact as the cause of the COVID‐19 pandemic. Its objective is to …

Eco-friendly cellulose-based nonionic antimicrobial polymers with excellent biocompatibility, nonleachability, and polymer miscibility

X Dang, Z Yu, X Wang, N Li - ACS Applied Materials & Interfaces, 2023 - ACS Publications
This study aims to prepare natural biomass-based nonionic antimicrobial polymers with
excellent biocompatibility, nonleachability, antimicrobial activity, and polymer miscibility …

Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells

M Farzanehpour, A Miri, AG Alvanegh… - Biochemical …, 2023 - Elsevier
The underlying cause of cancer is genetic disruption, so gene editing technologies,
particularly CRISPR/Cas systems can be used to go against cancer. The field of gene …