[HTML][HTML] Biomarker modeling of Alzheimer's disease
CR Jack, DM Holtzman - Neuron, 2013 - cell.com
Alzheimer's disease (AD) is a slowly progressing disorder in which pathophysiological
abnormalities, detectable in vivo by biomarkers, precede overt clinical symptoms by many …
abnormalities, detectable in vivo by biomarkers, precede overt clinical symptoms by many …
Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging
JE Ahlskog, YE Geda, NR Graff-Radford… - Mayo clinic …, 2011 - Elsevier
A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise,
may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords …
may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords …
The role of PARP1 in neurodegenerative diseases and aging
K Mao, G Zhang - The FEBS journal, 2022 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease
(PD), are characterized by progressive memory loss and motor impairment. Aging is a major …
(PD), are characterized by progressive memory loss and motor impairment. Aging is a major …
Identification of common variants associated with human hippocampal and intracranial volumes
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …
Brain structure and obesity
Obesity is associated with increased risk for cardiovascular health problems including
diabetes, hypertension, and stroke. These cardiovascular afflictions increase risk for …
diabetes, hypertension, and stroke. These cardiovascular afflictions increase risk for …
Early diagnosis of Alzheimer׳ s disease based on partial least squares, principal component analysis and support vector machine using segmented MRI images
Computer aided diagnosis (CAD) systems using functional and structural imaging
techniques enable physicians to detect early stages of the Alzheimer׳ s disease (AD). For …
techniques enable physicians to detect early stages of the Alzheimer׳ s disease (AD). For …
The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
[HTML][HTML] Biomarkers for the early detection and progression of Alzheimer's disease
The recent failures of potential disease-modifying drugs for Alzheimer's disease (AD) may
reflect the fact that the enrolled participants in clinical trials are already too advanced to …
reflect the fact that the enrolled participants in clinical trials are already too advanced to …
Structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with mild cognitive impairment
G Lombardi, G Crescioli, E Cavedo… - Cochrane Database …, 2020 - cochranelibrary.com
Background Mild cognitive impairment (MCI) due to Alzheimer's disease is the symptomatic
predementia phase of Alzheimer's disease dementia, characterised by cognitive and …
predementia phase of Alzheimer's disease dementia, characterised by cognitive and …
Impact of the Alzheimer's disease neuroimaging initiative, 2004 to 2014
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2015 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) was
established in 2004 to facilitate the development of effective treatments for Alzheimer's …
established in 2004 to facilitate the development of effective treatments for Alzheimer's …