Hypes, hopes, and the way forward for microalgal biotechnology

MJ Barbosa, M Janssen, C Südfeld, S D'Adamo… - Trends in …, 2023 - cell.com
The urge for food security and sustainability has advanced the field of microalgal
biotechnology. Microalgae are microorganisms able to grow using (sun) light, fertilizers …

Integrating plant molecular farming and materials research for next-generation vaccines

YH Chung, D Church, EC Koellhoffer, E Osota… - Nature Reviews …, 2022 - nature.com
Biologics—medications derived from a biological source—are increasingly used as
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …

Platforms for production of protein-based vaccines: from classical to next-generation strategies

R Cid, J Bolívar - Biomolecules, 2021 - mdpi.com
To date, vaccination has become one of the most effective strategies to control and reduce
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …

Plant-based COVID-19 vaccines: current status, design, and development strategies of candidate vaccines

PM Maharjan, S Choe - Vaccines, 2021 - mdpi.com
The prevalence of the coronavirus disease 2019 (COVID-19) pandemic in its second year
has led to massive global human and economic losses. The high transmission rate and the …

Plant‐specific glycosylation patterns in the context of therapeutic protein production

V Gomord, AC Fitchette… - Plant biotechnology …, 2010 - Wiley Online Library
While N‐glycan synthesis in the endoplasmic reticulum (ER) is relatively well conserved in
eukaryotes, N‐glycan processing and O‐glycan biosynthesis in the Golgi apparatus are …

Plant‐made vaccines for humans and animals

EP Rybicki - Plant biotechnology journal, 2010 - Wiley Online Library
The concept of using plants to produce high‐value pharmaceuticals such as vaccines is 20
years old this year and is only now on the brink of realisation as an established technology …

Advances in plant molecular farming

OO Obembe, JO Popoola, S Leelavathi… - Biotechnology advances, 2011 - Elsevier
Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are
engineered to produce recombinant pharmaceutical and industrial proteins in large …

Plant molecular farming of virus‐like nanoparticles as vaccines and reagents

EP Rybicki - Wiley Interdisciplinary Reviews: Nanomedicine …, 2020 - Wiley Online Library
The use of plants for the production of virus‐like nanoparticles (VNPs) dates back to
separating natural empty capsids of plant viruses from whole virions nearly 70 years ago …

[HTML][HTML] Molecular pharming—VLPs made in plants

J Marsian, GP Lomonossoff - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Transient expression is an effective method for the production of VLPs in
plants.•A number of VLPs, consisting of one or more proteins, have been produced.•Plant …

Alternative methods of vaccine delivery: an overview of edible and intradermal vaccines

E Criscuolo, V Caputo, RA Diotti… - Journal of …, 2019 - Wiley Online Library
Vaccines are recognized worldwide as one of the most important tools for combating
infectious diseases. Despite the tremendous value conferred by currently available vaccines …