Beyond cisplatin: New frontiers in metallodrugs for hard-to-treat triple negative breast cancer

N Muhammad, M Hanif, P Yang - Coordination Chemistry Reviews, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is the most aggressive and hard-to-treat form of breast
cancer. TNBC has a higher propensity for earlier relapse and an increased risk of metastasis …

[HTML][HTML] Anticancer properties of complexes derived from bidentate ligands

DI Ugwu, J Conradie - Journal of Inorganic Biochemistry, 2023 - Elsevier
Cancer is the abnormal division and multiplication of cells in an organ or tissue. It is the
second leading cause of death globally. There are various types of cancer such as prostate …

Anticancer potential of Cu (II) prolinedithiocarbamate complex: design, synthesis, spectroscopy, molecular docking, molecular dynamic, ADMET, and in-vitro studies

R Irfandi, I Raya, A Ahmad, A Fudholi… - Journal of …, 2023 - Taylor & Francis
Breast cancer continues to be a major health issue for women all over the world. Cancer
medications like cisplatin, which are widely used, still have negative side effects. The novel …

Study of new Zn (II) Prolinedithiocarbamate as a potential agent for breast cancer: Characterization and molecular docking

R Irfandi, S Santi, I Raya, A Ahmad, A Fudholi… - Journal of Molecular …, 2022 - Elsevier
This study characterized the synthetic Zn (II) Prolinedithiocarbamate and determined its anti-
cancer activity in vitro and in silico. Zn (II) Prolineditiocarbamate complex was synthesized …

Manganese (II) complexes of substituted salicylaldehydes and α-diimines: Synthesis, characterization and biological activity

S Ntanatsidis, S Perontsis, S Konstantopoulou… - Journal of Inorganic …, 2022 - Elsevier
The interaction of Mn+ 2 with substituted salicylaldehydes (X-saloH) led to the formation of
five manganese (II) complexes formulated as [Μn (X-salo) 2 (MeOH) 2]. When the reactions …

[HTML][HTML] The relationship between NFKB, HER2, ER expression and anthracycline-based neoadjuvan chemotherapy response in local advanced stadium breast …

C Manginstar, AA Islam, D Sampepajung… - Annals of Medicine and …, 2021 - Elsevier
Introduction Neoadjuvant chemotherapy has become the standard form of treatment for
locally advanced breast cancer. Chemoresistence is a problem that limits the effectiveness …

Anticancer Metallocenes and Metal Complexes of Transition Elements from Groups 4 to 7

I Kostova - Molecules, 2024 - mdpi.com
With the progression in the field of bioinorganic chemistry, the role of transition metal
complexes as the most widely used therapeutics is becoming a more and more attractive …

Interactions of Mn complexes with DNA: the relevance of therapeutic applications towards cancer treatment

OM Ganguly, S Moulik - Dalton Transactions, 2023 - pubs.rsc.org
Manganese (Mn) is one of the most significant bio-metals that helps the body to form
connective tissue, bones, blood clotting factors, and sex hormones. It is necessary for fat and …

Manganese Schiff base complexes, crystallographic studies, anticancer activities, and molecular docking

AT Odularu - Journal of Chemistry, 2022 - Wiley Online Library
Choice of ligands is significant to successful synthesis of metal complexes (coordination
compounds). This study reports the use of Schiff base as the right ligand to control the poor …

[HTML][HTML] A New Complex Design of Fe (II) Isoleucine Dithiocarbamate as a Novel Anticancer and Antivirus against SARSCOV-2 (COVID-19)

R Irfandi, R Riswandi, I Raya, A Ahmad… - Asian Pacific Journal …, 2022 - ncbi.nlm.nih.gov
Background: This study was carried out to synthesize a new complex of Fe (II) with
isoleucine dithiocarbamate ligand and to determine its potential as an anticancer and …