Steroids are small and highly important structural or signalling molecules in living organisms
and their metabolism is complex. Due to the multiplicity of enzymes involved there are many …

Traditional Chinese medicine (TCM) has been an indispensable source of drugs for curing
various human diseases. However, the inherent chemical diversity and complexity of TCM …

Liquid chromatography–tandem mass spectrometry (LC–MS/MS) is a powerful tool that is
changing the way we analyse steroids in the clinical laboratory. It is already opening up the …

For several decades now, the analysis of steroids has been a key tool in the diagnosis and
monitoring of numerous endocrine pathologies. Thus, the available methods used to …

Ion mobility spectrometry enhances the performance characteristics of liquid
chromatography–mass spectrometry workflows intended to steroid profiling by providing a …

Background Multi-steroid profiling is a powerful analytical tool that simultaneously quantifies
steroids from different biosynthetic pathways. Here we present an ultra-high performance …

Abstract An LC–MS/MS method was developed and validated to analyze simultaneously
estrogens (estradiol, E2; estrone, E1), androgens (testosterone, T; androstenedione, A4; …

Gas chromatography/mass spectrometry (GC/MS) has been used for steroid analysis since
the 1960s. The advent of protective derivatization, capillary columns, and inexpensive …

This study describes a validated LC–MS/MS method for assaying 23 steroids within a single
run from 150 μl of human plasma, serum or prostatic tissue homogenate. Isotope-labeled …

In recent years, the commercialization of hybrid ion mobility-mass spectrometers and their
integration in traditional LC-MS workflows provide new opportunities to extend the current …