Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
Targeting the DNA damage response in immuno-oncology: developments and opportunities
Immunotherapy has revolutionized cancer treatment and substantially improved patient
outcome with regard to multiple tumour types. However, most patients still do not benefit …
outcome with regard to multiple tumour types. However, most patients still do not benefit …
Advances in nanomaterials for photodynamic therapy applications: Status and challenges
Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to
radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although …
radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although …
[HTML][HTML] Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors
KM Heinhuis, W Ros, M Kok, N Steeghs, JH Beijnen… - Annals of …, 2019 - Elsevier
Background Cancer immunotherapy has changed the standard of care for a subgroup of
patients with advanced disease. Immune checkpoint blockade (ICB) in particular has shown …
patients with advanced disease. Immune checkpoint blockade (ICB) in particular has shown …
Metal drugs and the anticancer immune response
B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …
Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times
Monoclonal antibodies targeting programmed cell death 1/programmed cell death ligand 1
(PD-1/PD-L1) immune checkpoints have improved the treatments of cancers. However, not …
(PD-1/PD-L1) immune checkpoints have improved the treatments of cancers. However, not …
Cisplatin increases PD-L1 expression and optimizes immune check-point blockade in non-small cell lung cancer
The number of clinical protocols testing combined therapies including immune check-point
inhibitors and platinum salts is currently increasing in lung cancer treatment, however …
inhibitors and platinum salts is currently increasing in lung cancer treatment, however …
Insight on nano drug delivery systems with targeted therapy in treatment of oral cancer
Oral cancer is a type of cancer that develops in the mouth and is one of the deadliest
malignancies in the world. Currently surgical, radiation therapy, and chemotherapy are most …
malignancies in the world. Currently surgical, radiation therapy, and chemotherapy are most …
Nanoparticle‐based photothermal and photodynamic immunotherapy for tumor treatment
X Hou, Y Tao, Y Pang, X Li, G Jiang… - International journal of …, 2018 - Wiley Online Library
Nanoparticle‐based phototherapies, such as photothermal therapy (PTT) and photodynamic
therapy (PDT), exhibit strong efficacy, minimal invasion and negligible side effects in tumor …
therapy (PDT), exhibit strong efficacy, minimal invasion and negligible side effects in tumor …
Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action
Y Xue, S Gao, J Gou, T Yin, H He, Y Wang… - Expert opinion on …, 2021 - Taylor & Francis
Introduction Platinum chemotherapy is widely used in first-line treatment of patients with
various cancers. PD-1/PD-L1 inhibitors have shown efficacy in several cancers, and the …
various cancers. PD-1/PD-L1 inhibitors have shown efficacy in several cancers, and the …