The lysis of cells in order to extract the nucleic acids or proteins inside it is a crucial unit
operation in biomolecular analysis. This paper presents a critical evaluation of the various …

Effective and rapid point-of-care (POC) diagnostics have the capability to revolutionize
public healthcare both in developed and developing countries. One of the key challenges …

Cell lysis is an essential primary step in cell assays. In the process of cell lysis, the cell
membrane is destroyed and the substances inside the cell are extracted. By utilizing a …

Highly sensitive and specific pathogen diagnosis is essential for correct and timely treatment
of infectious diseases, especially virulent strains, in people. Point-of-care pathogen …

Urinary tract infections (UTIs) are one of the major burdens on public healthcare worldwide.
One of the primary causes of UTIs is the invasion of the urinary tract by uropathogenic …

Cell lysis is a key step for studying the structure and function of proteins in cells and an
important intermediate step in drug screening, cancer diagnosis, and genome analysis. The …

Bacterial foodborne diseases have become a growing global health concern, and nucleic
acid-based analysis is considered as a promising approach for rapid identification of …

Cell lysis is a critical step in genomics for the extraction of cellular components of
downstream assays. Electrical lysis (EL) offers key advantages in terms of speed and non …

This paper presents the design, microfabrication, and demonstration of a novel microfluidic
grinding mill for the lysis of the dinoflagellate, Alexandrium, a neurotoxin-producing genus of …

Transfection is a key function for many single-cell analyses. Reversible electroporation (EP)
using high intensity electric fields is a simple means of transfection applicable to most cell …