RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

In recent years, the RNA modification N6-methyladenosine (m6A) has been found to play a
role in the life cycles of numerous viruses and also in the cellular response to viral infection …

RNA tailing, or the addition of non-templated nucleotides to the 3′ end of RNA, is the most
frequent and conserved type of RNA modification. The addition of tails and their composition …

In virus–host interactions, nucleic acid‐directed first lines of defense that allow viral
clearance without compromising growth are of paramount importance. Plants use the RNA …

The endoplasmic reticulum (ER) coordinates mRNA translation and processing of secreted
and endomembrane proteins. ER-associated degradation (ERAD) prevents the …

Microbes associated with an organism can significantly modulate its susceptibility to viral
infections, but our understanding of the influence of individual microbes remains limited. The …

Strand selection is a critical step in microRNA (miRNA) biogenesis. Although the dominant
strand may change depending on cellular contexts, the molecular mechanism and …

In its natural habitat, C. elegans encounters a wide variety of microbes, including food,
commensals and pathogens. To be able to survive long enough to reproduce, C. elegans …

Innate immunity is the first line of host defense against pathogens. Here, through global
transcriptome and proteome analyses, we uncover that newly described cytoplasmic poly …