FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments

S Kaniyappan, K Tepper, J Biernat… - Molecular …, 2020 - Springer
Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of
several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau …

Novel antibody against low‐n oligomers of tau protein promotes clearance of tau in cells via lysosomes

RR Chandupatla, A Flatley, R Feederle… - … Research & Clinical …, 2020 - Wiley Online Library
Introduction Tau, a natively unfolded soluble protein, forms abnormal oligomers and
insoluble filaments in several neurodegenerative diseases, including Alzheimer disease …

The plasma factor XIII heterotetrameric complex structure: unexpected unequal pairing within a symmetric complex

S Singh, A Nazabal, S Kaniyappan, JL Pellequer… - Biomolecules, 2019 - mdpi.com
Factor XIII (FXIII) is a predominant determinant of clot stability, strength, and composition.
Plasma FXIII circulates as a pro-transglutaminase with two catalytic A subunits and two …