Human exposure to neurotoxic metals is a global public health problem. Metals which cause
neurological toxicity, such as lead (Pb) and manganese (Mn), are of particular concern due …

Occupational exposure to numerous individual chemicals has been associated with
olfactory dysfunction, mainly in individual case descriptions. Comprehensive …

Abstract Background The people of Bangladesh are currently exposed to high
concentrations of arsenic and manganese in drinking water, as well as elevated lead in …

Many chronic neurodegenerative disorders share a common pathogenic mechanism
involving the aggregation and deposition of misfolded proteins. Recently, it was shown that …

Increased manganese (Mn) exposure is known to cause cognitive, psychiatric and motor
deficits. Mn exposure occurs in different occupational settings, where the airborne Mn level …

Objectives Manganese exposure leads to diffuse cerebral metal deposition with the highest
concentration in the globus pallidus associated with increased T1-weighted MRI signal. T1 …

Background Nose-to-brain transport of airborne ultrafine particles (UFPs) via the olfactory
pathway has been verified as a possible route for particle translocation into the brain. The …

Manganese (Mn), an essential element to humans, in excess can cause neurotoxic damage.
So far, Mn exposure assessment has no ideal biomarker. This study aims to investigate the …

Objectives This preclinical study was designed to compare gadolinium (Gd) brain uptake
after repeated injections of a macrocyclic Gd-based contrast agent (GBCA)(gadoterate …

Natural leaching processes and/or anthropogenic contamination can result in ground water
concentrations of the essential metal manganese (Mn) that far exceed the current regulatory …