Telomere attrition is associated with increased morbidity and mortality of various age-related
diseases. Reports of association between telomere length (TL) and all-cause mortality …

Telomeres are the heterochromatic repeat regions at the ends of eukaryotic chromosomes,
whose length is considered to be a determinant of biological ageing. Normal ageing itself is …

The intestinal epithelium is maintained by a population of rapidly cycling (Lgr5+) intestinal
stem cells (ISCs). It has been postulated, however, that slowly cycling ISCs must also be …

Telomeres are nucleoprotein structures, located at the ends of chromosomes and are
subject to shortening at each cycle of cell division. They prevent chromosomal ends from …

As is the case with any metaphor, parental effects mean different things to different biologists—
from developmental induction of novel phenotypic variation to an evolved adaptation, and …

Leukocyte telomere length (LTL) is a complex genetic trait. It shortens with age and is
associated with a host of aging-related disorders. Recent studies have observed that …

Naturally, in somatic cells chromosome ends (telomeres) shorten during each cell division.
This process ensures to limit proliferation of somatic cells to avoid malignant proliferation; …

Telomeres, repetitive DNA sequences found at the ends of linear chromosomes, play a role
in regulating cellular proliferation, and shorten with increasing age in proliferating human …

The authors evaluated the effect of arsenic exposure on fetal and infant survival in a cohort
of 29,134 pregnancies identified by the health and demographic surveillance system in …

In multicellular organisms, telomerase is required to maintain telomere length in the
germline but is dispensable in the soma. Mice, for example, express telomerase in somatic …