Antimicrobial polymers: the potential replacement of existing antibiotics?

NF Kamaruzzaman, LP Tan, RH Hamdan… - International Journal of …, 2019 - mdpi.com
Antimicrobial resistance is now considered a major global challenge; compromising medical
advancements and our ability to treat infectious disease. Increased antimicrobial resistance …

Antimicrobial activities of conducting polymers and their composites

M Maruthapandi, A Saravanan, A Gupta, JHT Luong… - Macromol, 2022 - mdpi.com
Conducting polymers, mainly polyaniline (PANI) and polypyrrole (PPY) with positive charges
bind to the negatively charged bacterial membrane to interfere with bacterial activities. After …

State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections

A Cano, M Ettcheto, M Espina… - Journal of …, 2020 - Springer
Infectious diseases kill over 17 million people a year, among which bacterial infections stand
out. From all the bacterial infections, tuberculosis, diarrhoea, meningitis, pneumonia, sexual …

The chemistry and biology of guanidine natural products

RGS Berlinck, S Romminger - Natural Product Reports, 2016 - pubs.rsc.org
Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382 The present
review discusses the isolation, structure determination, synthesis, biosynthesis and …

An alternatingly amphiphilic, resistance-resistant antimicrobial oligoguanidine with dual mechanisms of action

Z Chen, C Zhou, Y Xu, K Wen, J Song, S Bai, C Wu… - Biomaterials, 2021 - Elsevier
The increasing number of infections caused by multi-drug resistance (MDR) bacteria is an
omen of a new global challenge. As one of the countermeasures under development …

Structure-function relationships of nonviral gene vectors: Lessons from antimicrobial polymers

H Xing, M Lu, T Yang, H Liu, Y Sun, X Zhao, H Xu… - Acta biomaterialia, 2019 - Elsevier
In recent years, substantial advances have been achieved in the design and synthesis of
nonviral gene vectors. However, lack of effective and biocompatible vectors still remains a …

Antimicrobial polymethacrylates based on quaternized 1, 3-thiazole and 1, 2, 3-triazole side-chain groups

R Tejero, D López, F López-Fabal… - Polymer …, 2015 - pubs.rsc.org
Polymers containing quaternary ammonium cations (QUATS) are well-known antimicrobial
and disinfectant agents. Mono-and bis-heterocyclic methacrylate monomers (MTAs) and …

Preparation and properties of pH-responsive, self-assembled colloidal nanoparticles from guanidine-containing polypeptide and chitosan for antibiotic delivery

YR Su, SH Yu, AC Chao, JY Wu, YF Lin, KY Lu… - Colloids and Surfaces A …, 2016 - Elsevier
Amoxicillin is a traditional antibiotic used to treat Helicobacter pylori (H. pylori). However, the
clinical applicability was limited by low local concentrations of amoxicillin that are reached at …

High efficiency antimicrobial thiazolium and triazolium side-chain polymethacrylates obtained by controlled alkylation of the corresponding azole derivatives

R Tejero, D López, F López-Fabal… - …, 2015 - ACS Publications
Two series of antimicrobial polymethacrylates (PMTAs) bearing mono and bis-cationic
quaternary ammonium cations (QUATs) were prepared by controlled N-alkylation of 1, 3 …

Elaboration of antimicrobial polymeric materials by dispersion of well-defined amphiphilic methacrylic SG1-based copolymers

BT Benkhaled, S Hadiouch, H Olleik, J Perrier… - Polymer …, 2018 - pubs.rsc.org
Bacterial resistance to antibiotics is a major public health problem and there is an urgent
need to find new antimicrobial materials to circumvent the development of resistant …