Semantic memory and language dysfunction in early Alzheimer's disease: a review

M Verma, RJ Howard - International journal of geriatric …, 2012 - Wiley Online Library
Background Language impairment in Alzheimer's disease occurs early, and language
function deteriorates with progression of the illness to cause significant disability. This …

The potential of functional MRI as a biomarker in early Alzheimer's disease

R Sperling - Neurobiology of aging, 2011 - Elsevier
Functional magnetic resonance imaging (fMRI) is a relative newcomer in the field of
biomarkers for Alzheimer's disease (AD). fMRI has several potential advantages, particularly …

[HTML][HTML] In vivo imaging of tau pathology using multi-parametric quantitative MRI

JA Wells, JM O'Callaghan, HE Holmes, NM Powell… - Neuroimage, 2015 - Elsevier
As the number of people diagnosed with Alzheimer's disease (AD) reaches epidemic
proportions, there is an urgent need to develop effective treatment strategies to tackle the …

[HTML][HTML] Hormone therapy at early post-menopause increases cognitive control-related prefrontal activity

R Girard, E Météreau, J Thomas, M Pugeat, C Qu… - Scientific reports, 2017 - nature.com
Clinical data have been equivocal and controversial as to the benefits to the brain and
cognition of hormone therapy (HT) in postmenopausal women. Recent reevaluation of the …

Beneficial effects of multisensory and cognitive stimulation on age-related cognitive decline in long-term-care institutions

TCG De Oliveira, FC Soares… - … Interventions in Aging, 2014 - Taylor & Francis
The aim of the present report was to evaluate the effectiveness and impact of multisensory
and cognitive stimulation on improving cognition in elderly persons living in long-term-care …

Clinical applications and future directions of functional MRI

DA Orringer, DR Vago, AJ Golby - Seminars in neurology, 2012 - thieme-connect.com
First described for use in mapping the human visual cortex in 1991, functional magnetic
resonance imaging (fMRI) is based on blood-oxygen level dependent (BOLD) changes in …

Using pictures and words to understand recognition memory deterioration in amnestic mild cognitive impairment and Alzheimer's disease: a review

BA Ally - Current neurology and neuroscience reports, 2012 - Springer
Difficulty recognizing previously encountered stimuli is one of the earliest signs of incipient
Alzheimer's disease (AD). Work over the last 10 years has focused on how patients with AD …

Age-related vulnerability in the neural systems supporting semantic processing

JE Peelle, K Chandrasekaran, J Powers… - Frontiers in aging …, 2013 - frontiersin.org
Our ability to form abstract representations of objects in semantic memory is crucial to
language and thought. The utility of this information relies both on the representations of …

Associative memory and underlying brain correlates in older adults with mild cognitive impairment

PC Chen, YL Chang - Neuropsychologia, 2016 - Elsevier
This study investigated associative recognition memory by using unique features of the
Chinese language and the underlying neuroanatomical correlates. The study participants …

Increased cerebral vascular reactivity in the tau expressing rTg4510 mouse: evidence against the role of tau pathology to impair vascular health in Alzheimer's …

JA Wells, HE Holmes, JM O'callaghan… - Journal of Cerebral …, 2015 - journals.sagepub.com
Vascular abnormalities are a key feature of Alzheimer's disease (AD). Imaging of cerebral
vascular reactivity (CVR) is a powerful tool to investigate vascular health in clinical …