Hypoxia is an essential hallmark of several serious diseases such as cardiovascular and
metabolic disorders and cancer. A decline in the tissue oxygen level induces hypoxic …

To date, extracellular vesicles (EVs) have been extensively investigated as potential
substitutes for cell therapy. Research has suggested their ability to overcome serious risks …

Exosomes are small extracellular vesicles that are secreted by almost all types of cells and
exist in almost all extracellular spaces. As an important mediator of intercellular …

Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of
proteins and RNAs for intercellular communication. With various biomolecules and specific …

Neutrophil extracellular traps (NETs) have been considered a significant unfavorable factor
for wound healing in diabetes, but the mechanisms remain unclear. The therapeutic …

Hypoxia is a central pathophysiological component in cancer, myocardial infarction and
ischemic stroke, which represent the most common medical conditions resulting in long-term …

Hypoxia induces changes in the secretion of extracellular vesicles (EVs) in several non‐
neuronal cells and pathological conditions. EVs are packed with biomolecules, such as …

Extracellular vesicles (EVs) are membrane enclosures released by eukaryotic cells that
carry bioactive molecules and serve to modulate biological responses in recipient cells. Both …

Background aims Although bone marrow-derived mesenchymal stromal cells (MSCs) have
demonstrated success in pre-clinical studies, they have shown only mild therapeutic effects …

Background Stem cell-derived extracellular vesicles (EVs) are an emerging class of
therapeutics with excellent biocompatibility, bioactivity and pro-regenerative capacity. One of …