Biopharmaceuticals are one of the most important groups of biotechnological products,
representing one‐quarter of all pharmaceutical sales and providing suitable and efficient …

MicroRNAs (miRNAs) are small non-coding RNAs that play important roles in many
biological processes such as development, cell signaling and immune response. Small RNA …

During cell infection, the fp25k gene of baculoviruses frequently mutates, producing the few
polyhedra (FP) per cell phenotype with reduced polyhedrin (polh) expression levels …

Polyhedra can encapsulate other proteins and have potential applications as protein
stabilizers. The extremely stable polyhedra matrix may provide a platform for future …

Bombyx mori nucleopolyhedrovirus (BmNPV) is an entomopathogenic virus of the family
Baculoviridae that causes disease in the silkworm, Bombyx mori, leading to a series of …

Packaging during the passaging of viruses in cell cultures yields various phenotypes and is
regulated by viral protein expression in infected cells. Although such a packaging …

Genome replication by the baculovirus DNA polymerase often generates errors in
mononucleotide repeat (MNR) sequences due to replication slippage. This results in the …

Baculovirus infection follows a transcriptionally controlled sequence of gene expression that
occurs by activation of different viral gene promoter sequences during infection. This …

Baculoviruses have two forms, occlusion derived virus (ODV) which is responsible for
primary infection in host midgut tissue and budded virus (BV), which infects all other host …

[目的] 苜蓿丫纹夜蛾核型多角体病毒(Autographacalifornicamulticapsidnucleopol…, AcMNPV)
在昆虫细胞中连续传代以后, 会出现从多多角体表型到少多角体表型的转变 …