Nuclear and radiological emergencies: biological effects, countermeasures and biodosimetry

E Obrador, R Salvador-Palmer, JI Villaescusa… - Antioxidants, 2022 - mdpi.com
Atomic and radiological crises can be caused by accidents, military activities, terrorist
assaults involving atomic installations, the explosion of nuclear devices, or the utilization of …

Genome-protecting compounds as potential geroprotectors

E Proshkina, M Shaposhnikov, A Moskalev - International journal of …, 2020 - mdpi.com
Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …

Applying productivity and phytonutrient profile criteria in modelling species selection of microgreens as Space crops for astronaut consumption

LG Izzo, C El Nakhel, Y Rouphael, S Proietti… - Frontiers in Plant …, 2023 - frontiersin.org
Introduction Long-duration missions in outer Space will require technologies to regenerate
environmental resources such as air and water and to produce food while recycling …

Radioprotectors, Radiomitigators, and Radiosensitizers

A Montoro, E Obrador, D Mistry, GI Forte, V Bravatà… - Radiobiology …, 2023 - Springer
This chapter gives an overview of molecules and mechanisms able to intervene with the
biological effects of ionizing radiation (IR), either related to their clinical use in radiotherapy …

Study logistics that can impact medical countermeasure efficacy testing in mouse models of radiation injury

AL DiCarlo, Z Perez Horta, CI Rios… - … journal of radiation …, 2021 - Taylor & Francis
Purpose To address confounding issues that have been noted in planning and conducting
studies to identify biomarkers of radiation injury, develop animal models to simulate these …

[HTML][HTML] Inter-agency perspective: Translating advances in biomarker discovery and medical countermeasures development between terrestrial and space radiation …

AL DiCarlo, LS Carnell, CI Rios… - Life sciences in space …, 2022 - Elsevier
Over the past 20+ years, the US Government has made significant strides in establishing
research funding and initiating a portfolio consisting of subject matter experts on radiation …

[HTML][HTML] High-throughput screening strategies for space-based radiation countermeasure discovery

KS Putt, Y Du, H Fu, ZY Zhang - Life Sciences in Space Research, 2022 - Elsevier
As humanity begins to venture further into space, approaches to better protect astronauts
from the hazards found in space need to be developed. One particular hazard of concern is …

Radioprotective effects of vitamin C, cimetidine, and famotidine on lipid peroxidase and hepatic glutathione levels in mouse liver

M Gholami, AA Ahmadi, R Yusofvand… - … journal of cell …, 2025 - Wiley Online Library
Radiation therapy is one of the most effective treatments for approximately 60% of patients
with cancer. During radiation exposure, the overproduction of reactive oxygen species …

Micronúcleos: Actualización del papel en la inestabilidad genética, inflamación, envejecimiento y cáncer. Revisión panorámica

O Torres-Bugarin, LF Arias-Ruiz - Revista Biomédica, 2023 - medigraphic.com
La integridad del genoma es esencial para la salud y la continuidad de las especies. Los
micronúcleos son biomarcadores de genotoxicidad, y protagonistas de inestabilidad y caos …

Nutraceuticals for Reducing Radiation Effects During Space Travel

S Kulkarni, D Gandhi, PJ Mehta - Handbook of Space Pharmaceuticals, 2022 - Springer
Abstract Space travel has advanced significantly in recent years. The deep space missions
and long-term exposures cause serious health risks to astronauts. Along with microgravity …