Harnessing nanomaterials for cancer sonodynamic immunotherapy

S Liang, J Yao, D Liu, L Rao, X Chen… - Advanced …, 2023 - Wiley Online Library
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …

Immune checkpoint inhibitors for the treatment of cancer: clinical impact and mechanisms of response and resistance

S Bagchi, R Yuan, EG Engleman - Annual Review of Pathology …, 2021 - annualreviews.org
Immune checkpoint inhibitors (ICIs) have made an indelible mark in the field of cancer
immunotherapy. Starting with the approval of anti-cytotoxic T lymphocyte-associated protein …

[HTML][HTML] PD-1/PD-L1 pathway: current researches in cancer

Y Han, D Liu, L Li - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
Cancer immunotherapy has been accompanied by promising results over the past few
years. Programmed Cell Death Protein 1 (PD-1) plays a vital role in inhibiting immune …

Ovarian cancer immunotherapy and personalized medicine

S Morand, M Devanaboyina, H Staats… - International Journal of …, 2021 - mdpi.com
Ovarian cancer response to immunotherapy is limited; however, the evaluation of
sensitive/resistant target treatment subpopulations based on stratification by tumor …

Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when …

HE Marei, A Hasan, G Pozzoli, C Cenciarelli - Cancer cell international, 2023 - Springer
Cancer is still the leading cause of death globally. The approval of the therapeutic use of
monoclonal antibodies against immune checkpoint molecules, notably those that target the …

Immune checkpoint proteins: Signaling mechanisms and molecular interactions in cancer immunotherapy

S Gaikwad, MY Agrawal, I Kaushik… - Seminars in cancer …, 2022 - Elsevier
Immune checkpoint proteins (ICP) are currently one of the most novel and promising areas
of immune-oncology research. This novel way of targeting tumor cells has shown favorable …

Copackaging photosensitizer and PD-L1 siRNA in a nucleic acid nanogel for synergistic cancer photoimmunotherapy

Y Guo, Q Zhang, Q Zhu, J Gao, X Zhu, H Yu, Y Li… - Science …, 2022 - science.org
Packaging multiple drugs into a nanocarrier with rational design to achieve synergistic
cancer therapy remains a challenge due to the intrinsically varied pharmacodynamics of …

Pathogenesis, clinical manifestations and complications of COVID-19

E Kordzadeh-Kermani, H Khalili… - Future microbiology, 2020 - Taylor & Francis
Aim: Despite the similarities in the pathogenesis of the beta coronaviruses, the precise
infective mechanisms of SARS-CoV-2 remain unclear. Objective: In this review, we aim to …

Single-cell RNA sequencing reveals that MYBL2 in malignant epithelial cells is involved in the development and progression of ovarian cancer

W Shao, Z Lin, Z Xiahou, F Zhao, J Xu, X Liu… - Frontiers in …, 2024 - frontiersin.org
Background Ovarian carcinoma (OC) is a prevalent gynecological malignancy associated
with high recurrence rates and mortality, often diagnosed at advanced stages. Despite …

Breast cancer in the era of precision medicine

N Sarhangi, S Hajjari, SF Heydari, M Ganjizadeh… - Molecular Biology …, 2022 - Springer
Breast cancer is a heterogeneous disorder with different molecular subtypes and biological
characteristics for which there are diverse therapeutic approaches and clinical outcomes …