[HTML][HTML] Updates on managements for keratoconus

M Mohammadpour, Z Heidari, H Hashemi - Journal of current …, 2018 - Elsevier
Purpose Keratoconus is a progressive disease of the cornea which can lead to blindness as
irregular astigmatism increases. Currently, a variety of methods are available for the …

Cytokine expression in keratoconus and its corneal microenvironment: a systematic review

RPL Wisse, JJW Kuiper, R Gans, S Imhof… - The ocular …, 2015 - Elsevier
Keratoconus (KC) is a progressive corneal ecstasia characterized by thinning and
weakening of the cornea that leads to a cone-like appearance, scarring, and decreased …

Genetic aspects of keratoconus: a literature review exploring potential genetic contributions and possible genetic relationships with comorbidities

E Loukovitis, K Sfakianakis, P Syrmakesi… - Ophthalmology and …, 2018 - Springer
Introduction Keratoconus (KC) is a complex, genetically heterogeneous, multifactorial
degenerative disorder that is accompanied by corneal ectasia which usually progresses …

TGFβ1 and TGFβ2 proteins in corneas with and without stromal fibrosis: delayed regeneration of apical epithelial growth factor barrier and the epithelial basement …

RC de Oliveira, G Tye, LP Sampaio, TM Shiju… - Experimental eye …, 2021 - Elsevier
The purpose of this study was to investigate the expression and localization of transforming
growth factor (TGF) β1 and TGFβ2 in rabbit corneas that healed with and without stromal …

Oxidative and antioxidative stress markers in keratoconus: a systematic review and meta‐analysis

V Navel, J Malecaze, B Pereira, JS Baker… - Acta …, 2021 - Wiley Online Library
Purpose To conduct a systematic review and meta‐analysis on the levels of oxidative stress
markers and antioxidants in keratoconus compared to healthy subject. Method The PubMed …

[HTML][HTML] Suppl-1, M8: Contact lenses for keratoconus-current practice

MM Moschos, E Nitoda, P Georgoudis… - The open …, 2017 - ncbi.nlm.nih.gov
Background: Keratoconus is a chronic, bilateral, usuallly asymmetrical, non-inflammatory,
ectatic disorder, being characterized by progressive steepening, thinning and apical …

[HTML][HTML] TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response

ZY Li, ZL Chen, T Zhang, C Wei, WY Shi - Aging (Albany NY), 2016 - ncbi.nlm.nih.gov
The corneal epithelium plays important roles in the maintenance of corneal transparency for
good vision, and acts as a protective barrier against foreign insults. Structural and functional …

In Vitro Expression Analysis of Cytokines and ROS-Related Genes in Human Corneal Fibroblasts and Keratocytes of Healthy and Keratoconus Corneas

T Berger, N Szentmáry, N Chai, E Flockerzi… - Ocular Immunology …, 2024 - Taylor & Francis
Purpose To investigate expression of cytokines and ROS-related genes in stromal cells of
healthy and keratoconus (KC) corneas. Methods Expression analysis was performed for …

Keratoconus detection by novel indices in patients with Down syndrome: a cohort population-based study

H Hashemi, M Miraftab, K Amanzadeh… - Japanese Journal of …, 2020 - Springer
Purpose To use novel indices to determine the prevalence of KC and its progression in
patients aged 10–30 years with Down syndrome. Study design Cohort population-based …

[HTML][HTML] Keratoconus in vitro and the key players of the TGF-β pathway

S Priyadarsini, TB McKay, A Sarker-Nag… - Molecular …, 2015 - ncbi.nlm.nih.gov
Purpose: Keratoconus (KC) is a corneal thinning disease of unknown etiology whose
pathophysiology is correlated with the presence of a thin corneal stroma and altered …