Animal models of schizophrenia

CA Jones, DJG Watson… - British journal of …, 2011 - Wiley Online Library
Developing reliable, predictive animal models for complex psychiatric disorders, such as
schizophrenia, is essential to increase our understanding of the neurobiological basis of the …

The mismatch negativity (MMN)–a unique window to disturbed central auditory processing in ageing and different clinical conditions

R Näätänen, T Kujala, C Escera, T Baldeweg… - Clinical …, 2012 - Elsevier
In this article, we review clinical research using the mismatch negativity (MMN), a change-
detection response of the brain elicited even in the absence of attention or behavioural task …

Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies

RG Steen, C Mull, R Mcclure, RM Hamer… - The British Journal of …, 2006 - cambridge.org
BackgroundStudies of people with schizophrenia assessed using magnetic resonance
imaging (MRI) usually include patients with first-episode and chronic disease, yet brain …

Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia

C Pantelis, M Yücel, SJ Wood, D Velakoulis… - Schizophrenia …, 2005 - academic.oup.com
The underlying neurobiology of emerging psychotic disorders is not well understood. While
there is evidence from structural imaging and other studies supporting the popular notion …

Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders

MJ Webster, MB Knable, J O'grady, J Orthmann… - Molecular …, 2002 - nature.com
Glucocorticoid receptors (GR) mediate the direct effects of glucocorticoids released in
response to stress and the regulation of the hypothalamic-pituitary-adrenocortical (HPA) …

Brain morphology in first-episode schizophrenia: a meta-analysis of quantitative magnetic resonance imaging studies

A Vita, L De Peri, C Silenzi, M Dieci - Schizophrenia research, 2006 - Elsevier
BACKGROUND: A number of meta-analytic reviews of structural brain imaging studies have
shown that multiple subtle brain abnormalities are consistently found in schizophrenia …

Progressive decrease of left Heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia: a longitudinal magnetic resonance imaging study

K Kasai, ME Shenton, DF Salisbury… - Archives of general …, 2003 - jamanetwork.com
Background The Heschl gyrus and planum temporale have crucial roles in auditory
perception and language processing. Our previous investigation using magnetic resonance …

Volumetric neuroimaging investigations in mood disorders: bipolar disorder versus major depressive disorder

JZ Konarski, RS McIntyre, SH Kennedy… - Bipolar …, 2008 - Wiley Online Library
Background: As patients with mood disorders manifest heterogeneity in phenomenology,
pathophysiology, etiology, and treatment response, a biological classification of mental …

Social cognition in schizophrenia: a review of face processing

K Marwick, J Hall - British Medical Bulletin, 2008 - academic.oup.com
Background People with schizophrenia have difficulties in interpreting social information.
Much social information is gathered from faces, and face processing represents a well …

Neuroanatomy of 'hearing voices': a frontotemporal brain structural abnormality associated with auditory hallucinations in schizophrenia

C Gaser, I Nenadic, HP Volz, C Büchel… - Cerebral …, 2004 - academic.oup.com
Auditory hallucinations are a frequent symptom in schizophrenia. While functional imaging
studies have suggested the association of certain patterns of brain activity with sub …