Sepsis is one of the main reasons for intensive care unit admission and is responsible for
high morbidity and mortality. The usual hemodynamic targets for resuscitation of patients …

Capillary refill time (CRT) is widely used by health care workers as part of the rapid,
structured cardiopulmonary assessment of critically ill patients. Measurement involves the …

Background The role of fluid resuscitation in the treatment of children with shock and life-
threatening infections who live in resource-limited settings is not established. Methods We …

Background Experimental and clinical studies have identified a crucial role of
microcirculation impairment in severe infections. We hypothesized that mottling, a sign of …

Background During septic shock management, the evaluation of microvascular perfusion by
skin analysis is of interest. We aimed to study the skin capillary refill time (CRT) in a selected …

Objective: The physical examination of peripheral perfusion based on touching the skin or
measuring capillary refill time has been related to the prognosis of patients with circulatory …

Background. Data from the largest randomized, controlled trial for the treatment of children
hospitalized with severe malaria were used to identify such predictors of a poor outcome …

Introduction The prognostic value of continuous monitoring of tissue oxygen saturation (StO
2) during early goal-directed therapy of critically ill patients has not been investigated. We …

Background Severe anaemia in children is a leading cause of hospital admission and a
major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood …

Importance Capillary refill time (CRT) is widely recommended as part of the routine
assessment of unwell children. Objective To determine the diagnostic value of capillary refill …