In recent years, an abundance of new molecular structures have been elucidated using cryo-
electron microscopy (cryo-EM), largely due to advances in hardware technology and data …

Cryo-electron microscopy (CryoEM) has become a vital technique in structural biology. It is
an interdisciplinary field that takes advantage of advances in biochemistry, physics, and …

Cryo-electron tomography (cryo-ET) enables molecular-resolution 3D imaging of complex
biological specimens such as viral particles, cellular sections and, in some cases, whole …

Electron microscopy of frozen hydrated samples (cryo-EM) is a powerful structural technique
that allows the direct study of functional macromolecular complexes in an almost …

We here introduce the third major release of the SIMPLE (Single-particle IMage Processing
Linux Engine) open-source software package for analysis of cryogenic transmission electron …

Highlights•Near-atomic resolution cryo-EM structures of challenging targets can now be
obtained.•Advances in sample preparation increases chance of high-resolution structure …

Cryogenic electron microscopy (cryo‐EM) and single‐particle analysis now enables the
determination of high‐resolution structures of macromolecular assemblies that have resisted …

Electron cryo-microscopy (cryo-EM) is a powerful method for investigating the structures of
protein molecules, with important implications for understanding the molecular processes of …

Recently, single-particle cryo-electron microscopy (cryo-EM) has become an indispensable
method for determining macromolecular structures at high resolution to deeply explore the …

Analysis of the three-dimensional (3D) structures of nanocrystals with solution-phase
transmission electron microscopy is beginning to reveal their unique physiochemical …