Voltage-gated sodium channels in cancers

H Liu, J Weng, CLH Huang, AP Jackson - Biomarker Research, 2024 - Springer
Voltage-gated sodium channels (VGSCs) initiate action potentials in electrically excitable
cells and tissues. Surprisingly, some VGSC genes are aberrantly expressed in a variety of …

A pan-cancer-bioinformatic-based literature review of TRPM7 in cancers

H Liu, JP Dilger, J Lin - Pharmacology & Therapeutics, 2022 - Elsevier
TRPM7, a divalent cation-selective channel with kinase domains, has been widely reported
to potentially affect cancers. In this study, we conducted multiple bioinformatic analyses …

Nanocrystals Slow-Releasing Ropivacaine and Doxorubicin to Synergistically Suppress Tumor Recurrence and Relieve Postoperative Pain

F Peng, J Liu, J Chen, W Wu, Y Zhang, G Zhao… - ACS …, 2023 - ACS Publications
Although surgical resection provides a straightforward and effective treatment for most
malignant solid tumors, tumor recurrence and acute postoperative pain continue to be two …

Genetic expression in cancer research: Challenges and complexity

H Liu, Z Guo, P Wang - Gene Reports, 2024 - Elsevier
Cancer research is profoundly influenced by the complex interplay of gene expression, yet
conventional studies often emphasize genes with high expression levels, potentially …

Is the voltage-gated sodium channel β3 subunit (SCN3B) a biomarker for glioma?

H Liu, J Weng, CLH Huang, AP Jackson - Functional & integrative …, 2024 - Springer
Recent studies suggest a need for reliable biomarkers enhancing prognosis prediction and
treatment strategies in cancer. Here, we performed a data analysis bearing on the …

Mechanisms of cancer inhibition by local anesthetics

Y Zhang, Y Jing, R Pan, K Ding, R Chen… - Frontiers in …, 2021 - frontiersin.org
The use of local anesthetics during surgical treatment of cancer patients is an important part
of perioperative analgesia. In recent years, it has been showed that local anesthetics can …

[HTML][HTML] Intraoperative lidocaine infusion in patients undergoing pancreatectomy for pancreatic cancer: a mechanistic, multicentre randomised clinical trial

H Zhang, M Qu, K Guo, Y Wang, J Gu, H Wu… - British journal of …, 2022 - Elsevier
Background Intravenous lidocaine has been postulated to improve long-term survival after
surgery for pancreatic cancer through anti-inflammatory effects, anti-tumour effects, or both …

Perioperative intravenous lidocaine and metastatic cancer recurrence-a narrative review

TP Wall, DJ Buggy - Frontiers in oncology, 2021 - frontiersin.org
Cancer is a major global health problem and the second leading cause of death worldwide.
When detected early, surgery provides a potentially curative intervention for many solid …

Chebulinic acid isolated from aqueous extracts of Terminalia chebula Retz inhibits Helicobacter pylori infection by potential binding to Cag A protein and regulating …

L Ou, Y Hao, H Liu, Z Zhu, Q Li, Q Chen, R Wei… - Frontiers in …, 2024 - frontiersin.org
Background Terminalia chebula Retz, known as the King of Tibet, is considered a functional
food in China, celebrated for its antioxidant, immune-modulating, antibacterial, and anti …

TRPM7 ion channel: Oncogenic roles and therapeutic potential in breast cancer

C Cordier, N Prevarskaya, V Lehen'kyi - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is the most frequently diagnosed malignant tumor and the
second leading cause of cancer death in women worldwide. The risk of developing breast …