JAK inhibitors in the treatment of atopic dermatitis

R Chovatiya, AS Paller - Journal of Allergy and Clinical Immunology, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin disorder associated with heterogenous
presentation and often immense patient burden. Safe, targeted treatment options are …

New treatments in atopic dermatitis

N Puar, R Chovatiya, AS Paller - Annals of Allergy, Asthma & Immunology, 2021 - Elsevier
Objective To discuss the efficacy and safety of novel and emerging topical and systemic
therapeutic agents for atopic dermatitis (AD). Data Sources The review of the published …

Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial

AS Paller, EL Simpson, EC Siegfried, MJ Cork… - The Lancet, 2022 - thelancet.com
Background Current systemic treatments for children younger than 6 years with moderate-to-
severe atopic dermatitis that is uncontrolled with topical therapies might have suboptimal …

[HTML][HTML] Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: a randomized, double …

AS Paller, EC Siegfried, D Thaçi, A Wollenberg… - Journal of the American …, 2020 - Elsevier
Background Children with severe atopic dermatitis (AD) have limited treatment options.
Objective We report the efficacy and safety of dupilumab+ topical corticosteroids (TCS) in …

Comparative efficacy and safety of systemic therapies used in moderate‐to‐severe atopic dermatitis: a systematic literature review and network meta‐analysis

JI Silverberg, JP Thyssen, K Fahrbach… - Journal of the …, 2021 - Wiley Online Library
Given the lack of head‐to‐head studies of systemic therapies in moderate‐to‐severe atopic
dermatitis (AD), network meta‐analyses (NMAs) can provide comparative efficacy and safety …

A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2

C Riggioni, P Comberiati, M Giovannini, I Agache… - Allergy, 2020 - Wiley Online Library
Abstract In December 2019, China reported the first cases of the coronavirus disease 2019
(COVID‐19). This disease, caused by the severe acute respiratory syndrome–related …

Biologics for treatment of atopic dermatitis: current status and future prospect

T Ratchataswan, TM Banzon, JP Thyssen… - The Journal of Allergy …, 2021 - Elsevier
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intense
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …

The molecular features of normal and atopic dermatitis skin in infants, children, adolescents, and adults

Y Renert-Yuval, E Del Duca, AB Pavel, M Fang… - Journal of Allergy and …, 2021 - Elsevier
Background Although atopic dermatitis (AD) often presents in infancy and persists into
adulthood, comparative characterization of AD skin among different pediatric age groups is …

Long-term efficacy and safety of dupilumab in adolescents with moderate-to-severe atopic dermatitis: results through week 52 from a phase III open-label extension …

A Blauvelt, E Guttman-Yassky, AS Paller… - American journal of …, 2022 - Springer
Background For adolescent patients (aged≥ 12 to< 18 years) with uncontrolled moderate-to-
severe atopic dermatitis (AD), 16 weeks of treatment with dupilumab resulted in substantial …

Dupilumab provides acceptable safety and sustained efficacy for up to 4 years in an open-label study of adults with moderate-to-severe atopic dermatitis

LA Beck, M Deleuran, R Bissonnette… - American journal of …, 2022 - Springer
Background Moderate‐to‐severe atopic dermatitis (AD) often requires long-term
management with systemic therapies. Objective Our objective was to report the safety and …