Laboratory evaluation of pheochromocytoma and paraganglioma

G Eisenhofer, M Peitzsch - Clinical chemistry, 2014 - academic.oup.com
BACKGROUND Pheochromocytomas and paragangliomas (PPGLs) are potentially lethal
yet usually surgically curable causes of endocrine hypertension; therefore, once clinical …

[HTML][HTML] Reference intervals for LC-MS/MS measurements of plasma free, urinary free and urinary acid-hydrolyzed deconjugated normetanephrine, metanephrine and …

G Eisenhofer, M Peitzsch, D Kaden, K Langton… - Clinica chimica acta, 2019 - Elsevier
Background Plasma or urinary metanephrines are recommended for screening of
pheochromocytomas and paragangliomas (PPGLs). Measurements of urinary free rather …

Simultaneous liquid chromatography tandem mass spectrometric determination of urinary free metanephrines and catecholamines, with comparisons of free and …

M Peitzsch, D Pelzel, S Glöckner, A Prejbisz… - Clinica Chimica …, 2013 - Elsevier
OBJECTIVE: We introduce a novel liquid chromatographic tandem-mass spectrometric
method for simultaneous measurements of urinary catecholamines and their free O …

Simple, rapid, and cost-effective microextraction by the packed sorbent method for quantifying of urinary free catecholamines and metanephrines using liquid …

X Xiong, Y Zhang - Analytical and bioanalytical chemistry, 2020 - Springer
Pheochromocytoma and paraganglioma (PPGL) are rare neuroendocrine tumors arising
from adrenal and extra-adrenal chromaffin cells. They produce excessive amounts of …

Quantitation using HRMS: A new tool for rapid, specific and sensitive determination of catecholamines and deconjugated methanephrines metanephrines in urine

S Lefeuvre, J Bois-Maublanc, E Mongeois… - … of Chromatography B, 2021 - Elsevier
Urinary catecholamines and their methylated metabolites are biochemical indicators of
pheochromocytoma, paraganglioma and neuroblastoma. A rapid and precise analytical …

Synthesis and characterization of octopamine sulfate, norfenefrine sulfate and etilefrine sulfate reference materials for doping control

SJ Kalita, SD Pawar, P Vernekar… - Journal of Chemical …, 2023 - Wiley Online Library
BACKGROUND Doping is the use of prohibited substances by athletes to improve their
performance. World Anti‐Doping Agency (WADA)‐accredited laboratories require various …

Enzyme and acid deconjugation of plasma sulfated metanephrines

M Glauser, M Metrailler, S Gerber-Lemaire… - Clinica Chimica …, 2014 - Elsevier
Background Total (ie free+ sulfated) metanephrines in plasma is a biomarker for the
diagnosis of pheochromocytoma/paraganglioma. Sulfated metanephrines must be …

Preservation of urine free catecholamines and their free O-methylated metabolites with citric acid as an alternative to hydrochloric acid for LC-MS/MS-based analyses

M Peitzsch, D Pelzel, P Lattke, G Siegert… - Clinical Chemistry and …, 2016 - degruyter.com
Background: Measurements of urinary fractionated metadrenalines provide a useful
screening test to diagnose phaeochromocytoma. Stability of these compounds and their …

Stanovení volného 3-methoxytyraminu pomocí LC-MS/MS u dětí s neuroblastomem

M Mellová, K Dunovská, A Vícha, J Čepová… - Chemické …, 2025 - chemicke-listy.cz
Neuroblastomas are the most common solid tumours in early childhood. Currently, the
prognosis of patients is evaluated almost exclusively on the basis of molecular-genetic …

Urinary free metanephrines and suitability of available quality control material

AS Davison - Clinica chimica acta; international journal of …, 2013 - pubmed.ncbi.nlm.nih.gov
Keywords: EQA; HPLC-ECD; IQC; LC-MS/MS; PCC; UMets; external quality assurance; high
performance liquid chromatography with electrochemical detection; internal quality control; …