The importance of immune gene variability (MHC) in evolutionary ecology and conservation

S Sommer - Frontiers in zoology, 2005 - Springer
Genetic studies have typically inferred the effects of human impact by documenting patterns
of genetic differentiation and levels of genetic diversity among potentially isolated …

Rapid evolutionary dynamics and disease threats to biodiversity

S Altizer, D Harvell, E Friedle - Trends in Ecology & Evolution, 2003 - cell.com
Existing and emerging pathogens pose unusual challenges for conservation because of
their potential to drive rapid changes in the numerical abundance and genetic composition …

[图书][B] Infectious diseases in primates: behavior, ecology and evolution

C Nunn, S Altizer - 2006 - books.google.com
Recent progress in the field of wildlife disease ecology demonstrates that infectious disease
plays a crucial role in the lives of wild animals. Parasites and pathogens should be …

[HTML][HTML] Pathogen-driven selection and worldwide HLA class I diversity

F Prugnolle, A Manica, M Charpentier, JF Guégan… - Current biology, 2005 - cell.com
The human leukocyte antigen (HLA; known as MHC in other vertebrates) plays a central role
in the recognition and presentation of antigens to the immune system and represents the …

Perspective: detecting adaptive molecular polymorphism: lessons from the MHC

D Garrigan, PW Hedrick - Evolution, 2003 - Wiley Online Library
In the 1960s, when population geneticists first began to collect data on the amount of genetic
variation in natural populations, balancing selection was invoked as a possible explanation …

SSCP is not so difficult: the application and utility of single‐stranded conformation polymorphism in evolutionary biology and molecular ecology

P Sunnucks, ACC Wilson, LB Beheregaray… - Molecular …, 2000 - Wiley Online Library
All genetic markers are estimators of DNA nucleotide sequence variation. Rather than
obtaining DNA sequence data, it is cheaper and faster to use techniques that estimate …

Methods for MHC genotyping in non‐model vertebrates

W Babik - Molecular ecology resources, 2010 - Wiley Online Library
Genes of the major histocompatibility complex (MHC) are considered a paradigm of
adaptive evolution at the molecular level and as such are frequently investigated by …

Major histocompatibility complex (MHC) markers in conservation biology

B Ujvari, K Belov - International Journal of Molecular Sciences, 2011 - mdpi.com
Human impacts through habitat destruction, introduction of invasive species and climate
change are increasing the number of species threatened with extinction. Decreases in …

Geographic heterogeneity in natural selection on an MHC locus in sockeye salmon

KM Miller, KH Kaukinen, TD Beacham, RE Withler - Genetica, 2001 - Springer
Balancing selection maintains high levels of polymorphism and heterozygosity in genes of
the MHC (major histocompatibility complex) of vertebrate organisms, and promotes long …

An Update on Status and Conservation of the Przewalski's Horse (Equus ferus przewalskii): Captive Breeding and Reintroduction Projects

MA Turghan, Z Jiang, Z Niu - Animals, 2022 - mdpi.com
Simple Summary The Przewalski's horse (Equus ferus przewalskii), the only extant species
of wild horse, was extinct in the wild in 1960s. The wild horse has been successfully saved …