In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

Over the past decades, the bulk of chemists' interests have been on heterocyclic compounds
and their various derivatives as well as their applications in the pharmaceutical and …

Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …

Abstract Imidazo [2, 1-b][1, 3, 4] thiadiazole heterocycle was discovered during the 1950s.
Since then, many newer derivatives are being developed and evaluated for their biological …

Two series of Benzimidazole clubbed with triazolo-thiadiazoles (5a–q, 5r, 5s and 5x–a1)
and triazolo-thiadiazines (5t–w) were synthesized with an aim to produce promising …

Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …

Abstract A series of imidazo [2, 1-b] thiazoles bearing pyrazole moieties 4–6 (a–c) was
synthesized through the reaction of 6-hydrazinylimidazo [2, 1-b] thiazoles 3a–c with different …

Fused heterobicyclic systems have gained much importance in the field of medicinal
chemistry because of their broad spectrum of physiological activities. Among the …

(3-Chlorophenyl)-1, 3, 4-thiadiazol-2-amine 2 was synthesized and employed to synthesize
new 1, 3, 4-thiadiazole and 1, 3, 4-thiadiazolo [3, 2-a] pyrimidine derivatives via reactions …