The mechanism and therapy of aortic aneurysms

J Gao, H Cao, G Hu, Y Wu, Y Xu, H Cui, HS Lu… - Signal transduction and …, 2023 - nature.com
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Cytokines in abdominal aortic aneurysm: master regulators with clinical application

OA Puchenkova, VO Soldatov, AE Belykh… - Biomarker …, 2022 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disorder with a mostly
asymptomatic course where the abdominal aorta is weakened and bulged. Cytokines play …

Cellular, Molecular and Clinical Aspects of Aortic Aneurysm—Vascular Physiology and Pathophysiology

D Domagała, K Data, H Szyller, M Farzaneh… - Cells, 2024 - mdpi.com
A disturbance of the structure of the aortic wall results in the formation of aortic aneurysm,
which is characterized by a significant bulge on the vessel surface that may have …

[HTML][HTML] Immune checkpoint programmed death-1 mediates abdominal aortic aneurysm and pseudoaneurysm progression

P Sun, L Zhang, Y Gu, S Wei, Z Wang, M Li… - Biomedicine & …, 2021 - Elsevier
Purpose The causes and pathogenetic mechanisms underlying abdominal aortic aneurysms
(AAAs) and pseudoaneurysms are not fully understood. We hypothesized that inhibiting …

Sea cucumber peptides inhibit the malignancy of NSCLC by regulating miR-378a-5p targeted TUSC2

J Mao, Z Zhang, Y Chen, T Wu, V Fersht, Y Jin… - Food & Function, 2021 - pubs.rsc.org
Lung cancer is a common cancer with high mortality worldwide, and non-small cell lung
cancer (NSCLC) accounts for the majority. The clinical treatment effect of NSCLC is not …

A systematic review of the cardiometabolic benefits of plant products containing mixed phenolics and polyphenols in postmenopausal women: Insufficient evidence for …

L Sanchez-Martinez, MJ Periago, J Garcia-Alonso… - Nutrients, 2021 - mdpi.com
Menopause is characterized by endocrine and physiological changes and is often
accompanied by increased body weight and cholesterol, glucose intolerance, and/or …

Obesity and the obesity paradox in abdominal aortic aneurysm

F Lu, Y Lin, J Zhou, Z Chen, Y Liu, M Zhong… - Frontiers in …, 2024 - frontiersin.org
Obesity, characterized by its complexity and heterogeneity, has emerged as a significant
public health concern. Its association with increased incidence and mortality of …

An Exploratory Critical Review on TNF-α as a Potential Inflammatory Biomarker Responsive to Dietary Intervention with Bioactive Foods and Derived Products

S Quarta, M Massaro, MA Carluccio, N Calabriso… - Foods, 2022 - mdpi.com
This review collects and critically examines data on the levels of tumour necrosis factor-
alpha (TNF-α) in lean, overweight and obese subjects, and the effects of intervention with …

[HTML][HTML] Glutamine Protects against Mouse Abdominal Aortic Aneurysm through Modulating VSMC Apoptosis and M1 Macrophage Activation

J Wang, X Da, Y Chen, A Yuan, J Pu - International Journal of …, 2024 - ncbi.nlm.nih.gov
Glutamine (Gln), known as the most abundant free amino acid, is widely spread in human
body. In this study, we demonstrated the protective effects of glutamine against mouse …

Identification and experimental validation of autophagy-related genes in abdominal aortic aneurysm

X Yuan, Y Song, H Xin, L Zhang, B Liu, J Ma… - European Journal of …, 2023 - Springer
Aim Autophagy plays essential roles in abdominal aortic aneurysm (AAA) development and
progression. The objective of this study was to verify the autophagy-related genes (ARGs) …