Immunopsychiatric field has rapidly accumulated evidence demonstrating the involvement of
both innate and adaptive immune components in psychotic disorders such as …

Meta-analyses of cross-sectional studies suggest that patients with psychosis have higher
circulating levels of C-reactive protein (CRP) compared with healthy controls; however …

Intravital microscopy (IVM) is a powerful technique that enables imaging of internal tissues at
(sub) cellular resolutions in living animals. Here, we present a silicone-based imaging …

C-reactive protein (CRP) and inflammatory ratios have been proposed to study immune
dysregulation in schizophrenia. Nevertheless, links between CRP and inflammatory ratios in …

Around a quarter of people who experience a first episode of psychosis (FEP) will develop
treatment-resistant schizophrenia, but there are currently no established clinically useful …

Background Positive associations between the risk of schizophrenia and the level of white
blood cells (WBC) count have been suggested by observational studies. However, the …

A complete blood count (CBC) is a routinely performed blood examination. Only a few
studies assess the relationship between CBC and oxidative stress (OS) in schizophrenia …

Background Persistent anxiety in childhood and adolescence could represent a novel
treatment target for psychosis, potentially targeting activation of stress pathways and …

Background Systemic, low-grade immune–inflammatory activity, together with social and
neurocognitive performance deficits are a transdiagnostic trait of people suffering from type …

Depression and psychosis have a developmental component to their origin. Epidemiologic
evidence, which we synthesize in this nonsystematic review, suggests that early-life …