Recent coating developments for combination devices in orthopedic and dental applications: A literature review

EJ Tobin - Advanced Drug Delivery Reviews, 2017 - Elsevier
Orthopedic and dental implants have been used successfully for decades to replace or
repair missing or damaged bones, joints, and teeth, thereby restoring patient function …

A review of topical phage therapy for chronically infected wounds and preparations for a randomized adaptive clinical trial evaluating topical phage therapy in …

CA Duplessis, B Biswas - Antibiotics, 2020 - mdpi.com
The advent and increasing prevalence of antimicrobial resistance commensurate with the
absence of novel antibiotics on the horizon raises the specter of untreatable infections …

Phage Therapy for Limb-threatening Prosthetic Knee Klebsiella pneumoniae Infection: Case Report and In Vitro Characterization of Anti-biofilm Activity

EJ Cano, KM Caflisch, PL Bollyky… - Clinical Infectious …, 2021 - academic.oup.com
Background Prosthetic joint infection (PJI) is a potentially limb-threatening complication of
total knee arthroplasty. Phage therapy is a promising strategy to manage such infections …

Iodine Immobilized Metal–Organic Framework for NIR‐Triggered Antibacterial Therapy on Orthopedic Implants

W Teng, Z Zhang, Y Wang, Y Ye, E Yinwang, A Liu… - Small, 2021 - Wiley Online Library
Iodine has been known as an effective disinfectant with broad‐spectrum antimicrobial
potency yet without drug resistance risk when used in clinic. However, the exploration of …

Refractory Pseudomonas Bacteremia in a 2-Year-Old Sterilized by Bacteriophage Therapy

C Duplessis, B Biswas, B Hanisch… - Journal of the …, 2018 - academic.oup.com
Here, we report a complex case that involved a pediatric patient who experienced
recalcitrant multidrug-resistant Pseudomonas aeruginosa infection complicated by …

Metagenomic next-generation sequencing of synovial fluid demonstrates high accuracy in prosthetic joint infection diagnostics: mNGS for diagnosing PJI

Z Huang, W Li, GC Lee, X Fang, L Xing… - Bone & Joint …, 2020 - boneandjoint.org.uk
Aims The aim of this study was to evaluate the performance of metagenomic next-generation
sequencing (mNGS) in detecting pathogens from synovial fluid of prosthetic joint infection …

The serum level of C-reactive protein alone cannot be used for the diagnosis of prosthetic joint infections, especially in those caused by organisms of low virulence

D Akgün, M Müller, C Perka… - The bone & joint journal, 2018 - boneandjoint.org.uk
Aims The aim of this study was to determine the prevalence and characteristics of C-reactive
protein (CRP)-negative prosthetic joint infection (PJI) and evaluate the influence of the type …

Challenges in the microbiological diagnosis of implant-associated infections: A summary of the current knowledge

A Oliva, MC Miele, D Al Ismail, F Di Timoteo… - Frontiers in …, 2021 - frontiersin.org
Implant-associated infections are characterized by microbial biofilm formation on implant
surface, which renders the microbiological diagnosis challenging and requires, in the …

Pathogenic detection by metagenomic next-generation sequencing in osteoarticular infections

Z Huang, Z Zhang, B Yang, W Li, C Zhang… - Frontiers in cellular …, 2020 - frontiersin.org
Objectives: To evaluate metagenomic next-generation sequencing (mNGS) as a diagnostic
tool in detecting pathogens from osteoarticular infection (OAI) samples. Methods: 130 …

Biofilms in periprosthetic joint infections: a review of diagnostic modalities, current treatments, and future directions

MM Shoji, AF Chen - The Journal of Knee Surgery, 2020 - thieme-connect.com
As the number of total joint arthroplasties continues to rise, periprosthetic joint infection (PJI),
a significant and devastating complication of total joint arthroplasty, may also increase. In …