Soil organic matter is the dominant carbon pool in terrestrial ecosystems, and its
management is of increasing policy relevance. Soil microbes are the main drivers of soil …

Facing frequent phage challenges, bacteria have evolved numerous mechanisms to resist
phage infection. A commonly used phage resistance strategy is abortive infection (Abi), in …

During the past 85 years of antibiotic use, we have learned a great deal about how these
'miracle'drugs work. We know the molecular structures and interactions of these drugs and …

CRISPR–Cas is a widespread adaptive immune system in bacteria and archaea that
protects against viral infection by targeting specific invading nucleic acid sequences …

Due to the increasing bacterial resistance to conventional antibiotics, developing safe and
effective approaches to combat infections caused by bacteria and biofilms has become an …

Acute methicillin resistant Staphylococcus aureus (MRSA) pneumonia is one of the most
frequently seen lung infection diseases with high morbidity and mortality. It is urgent to …

Bacterial genomes are highly plastic allowing the generation of variants through mutations
and acquisition of genetic information. The fittest variants are then selected by the econiche …

Although antimicrobial peptides (AMPs) have become powerful drug candidates in the post-
antibiotic era, but their low protease stability hinders their clinical application. In the present …

The growing demand for titanium-based implants and the subsequent rise in implant-
associated infections necessitate novel developments in anti-infective technologies. Recent …

Colorectal cancer (CRC) is one of the most prevalent and deadly malignancies that can be
influenced by Fusobacterium nucleatum (Fn), a bacterium that promotes tumor development …