Sirtuins, also called silent information regulator 2, are enzymes that rely on nicotinamide
adenine dinucleotide (NAD+) to function as histone deacetylases. Further investigation is …

Patterns of transcriptional activity are encoded in our genome through regulatory elements
such as promoters or enhancers that, paradoxically, contain similar assortments of …

Over the past decade, there has been a surge in discoveries of how metabolic pathways
regulate immune cell function in health and disease, establishing the field of …

Zika virus (ZIKV) infection during pregnancy threatens pregnancy and fetal health. However,
the infectivity and pathological effects of ZIKV on placental trophoblast progenitor cells in …

Zika virus (ZIKV) infection is a global public health concern linked to adult neurological
disorders and congenital diseases in newborns. Host lipid metabolism, including lipid …

In recent decades, mosquito-borne illnesses have emerged as a major health burden in
many tropical regions. These diseases, such as malaria, dengue fever, chikungunya, yellow …

Zika virus (ZIKV) infection during pregnancy causes severe neurological and ocular
abnormalities in infants, yet no vaccine or antivirals are available. Our transcriptomic …

Zika virus (ZIKV) is a mosquito-borne flavivirus that caused an epidemic in the Americas in
2016 and is linked to severe neonatal birth defects, including microcephaly and …

Unstable transcripts have emerged as markers of active enhancers in vertebrates and
shown to be involved in many cellular processes and medical disorders. However, their …

Zika virus is a member of the Flaviviridae family that has caused recent outbreaks
associated with neurological malformations. Transmission of Zika virus occurs primarily via …